Loratadine Impurity 2

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Names

[ CAS No. ]:
31251-41-9

[ Name ]:
Loratadine Impurity 2

[Synonym ]:
8-Chloro-10
D] cycloheptan-5-one
8-Chloro-10,11-dihydro-4-aza-5
MFCD00800222
Loratadine Impurity 2

Chemical & Physical Properties

[ Density]:
1.313g/cm3

[ Boiling Point ]:
433.6ºC at 760mmHg

[ Melting Point ]:
90-92ºC

[ Molecular Formula ]:
C₁₄H₁₀ClNO

[ Molecular Weight ]:
243.68800

[ Flash Point ]:
216ºC

[ Exact Mass ]:
243.04500

[ PSA ]:
29.96000

[ LogP ]:
3.06460

[ Index of Refraction ]:
1.632

[ Storage condition ]:
-20?C Freezer

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Loratadine Impurity 18
3-[2-(3-chlorophenyl)ethyl]pyridine-2-carboxylic acid,hydrochloride
N-phenyl-3-[2-(3-chlorophenyl)ethyl]-2-pyridine carboxamide
Carbon
Phosphorus pentachloride
3,5-dichloro-2-iodobenzoic acid
(5-chloro-2-iodophenyl)methanol
2-(Bromomethyl)-4-chloro-1-iodobenzene
3-(5-chloro-2-iodophenethyl)-N-phenylpicolinamide

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%