Loratadine Impurity 2

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Names

[ CAS No. ]:
31251-41-9

[ Name ]:
Loratadine Impurity 2

[Synonym ]:
8-Chloro-10
D] cycloheptan-5-one
8-Chloro-10,11-dihydro-4-aza-5
MFCD00800222
Loratadine Impurity 2

Chemical & Physical Properties

[ Density]:
1.313g/cm3

[ Boiling Point ]:
433.6ºC at 760mmHg

[ Melting Point ]:
90-92ºC

[ Molecular Formula ]:
C14H10ClNO

[ Molecular Weight ]:
243.68800

[ Flash Point ]:
216ºC

[ Exact Mass ]:
243.04500

[ PSA ]:
29.96000

[ LogP ]:
3.06460

[ Index of Refraction ]:
1.632

[ Storage condition ]:
-20?C Freezer

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Loratadine Impurity 18
  • 3-[2-(3-chlorophenyl)ethyl]pyridine-2-carboxylic acid,hydrochloride
  • N-phenyl-3-[2-(3-chlorophenyl)ethyl]-2-pyridine carboxamide
  • Carbon
  • Phosphorus pentachloride
  • 3,5-dichloro-2-iodobenzoic acid
  • (5-chloro-2-iodophenyl)methanol
  • 2-(Bromomethyl)-4-chloro-1-iodobenzene
  • 3-(5-chloro-2-iodophenethyl)-N-phenylpicolinamide

DownStream

  • Loratadine Impurity 14
  • N-Methyl Desloratadine
  • Loratadine
  • Desloratadine
  • 5-Hydroxy Desloratadine
  • 6-Hydroxy Desloratadine

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • Loratadine Impurity 20
  • Loratadine Impurity 21
  • Loratadine Impurity 24
  • Loratadine Impurity 26
  • Loratadine Impurity 25
  • Loratadine Impurity 23
  • 2-(3-benzyl-8-methyl-4-oxo-3H-pyrimido[5,4-b]indol-5(4H)-yl)-N-(3-chloro-4-methoxyphenyl)acetamide
  • 2-(3-benzyl-8-methyl-4-oxo-3H-pyrimido[5,4-b]indol-5(4H)-yl)-N-mesitylacetamide
  • 2-(3-benzyl-8-methyl-4-oxo-3H-pyrimido[5,4-b]indol-5(4H)-yl)-N-(5-chloro-2-methylphenyl)acetamide
  • 2-(3-benzyl-8-methyl-4-oxo-3H-pyrimido[5,4-b]indol-5(4H)-yl)-N-(2,4-dimethylphenyl)acetamide
  • 2-(3-benzyl-8-methyl-4-oxo-3H-pyrimido[5,4-b]indol-5(4H)-yl)-N-(2-chloro-4-methylphenyl)acetamide
  • N-benzyl-2-(3-(4-methoxybenzyl)-8-methyl-4-oxo-3H-pyrimido[5,4-b]indol-5(4H)-yl)acetamide
  • N-Methyl-N-(3-methylenecyclobutyl)amine
  • N-(2-chlorobenzyl)-2-(3-(4-methoxybenzyl)-8-methyl-4-oxo-3H-pyrimido[5,4-b]indol-5(4H)-yl)acetamide
  • 2-(3-(4-methoxybenzyl)-8-methyl-4-oxo-3H-pyrimido[5,4-b]indol-5(4H)-yl)-N-phenethylacetamide
  • N-(4-ethylphenyl)-2-(3-(4-methoxybenzyl)-8-methyl-4-oxo-3H-pyrimido[5,4-b]indol-5(4H)-yl)acetamide
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