Loratadine Impurity 18

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Names

[ CAS No. ]:
31255-57-9

[ Name ]:
Loratadine Impurity 18

[Synonym ]:
MFCD02942420
3-[2-(3-Chlorophenyl)ethyl]-2-pyridinecarbonitrile
Loratadine Impurity 18

Chemical & Physical Properties

[ Density]:
1.23 g/cm3

[ Boiling Point ]:
375.7ºC at 760 mmHg

[ Melting Point ]:
71-72ºC

[ Molecular Formula ]:
C14H11ClN2

[ Molecular Weight ]:
242.70400

[ Flash Point ]:
181ºC

[ Exact Mass ]:
242.06100

[ PSA ]:
36.68000

[ LogP ]:
3.39188

[ Index of Refraction ]:
1.605

[ Storage condition ]:
Refrigerator

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-(3-CHLOROPHENYLETHYL)PYRIDINE N-OXIDE
  • Sodium cyanide
  • 3-[2-(3-CHLORO-PHENYL)-ETHYL]-PYRIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE
  • N-tert-butyl-3-methylpyridine-2-carboxamide
  • m-Chlorbenzyl chloride
  • 2-Cyano-3-methylpyridine

DownStream

  • Loratadine Impurity 2
  • N-Methyl Desloratadine
  • Loratadine
  • Desloratadine
  • (3-(3-CHLOROPHENETHYL)PYRIDIN-2-YL)(1-METHYLPIPERIDIN-4-YL)METHANONE HYDROCHLORIDE
  • (1-Methyl-4-piperidinyl) {3[2-(3-chlorophenyl) ethyl ]2-pyridinyl} methanone
  • Sch 37370

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • Desloratadine Impurity 18
  • Loratadine Impurity 3
  • Loratadine Impurity I
  • Loratadine Impurity 8
  • Loratadine Impurity 1
  • Loratadine Impurity 16
  • 1-(Dimethyl-1,3-thiazol-2-yl)-3-methoxypropan-1-one
  • 2-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanoyl]-2-azabicyclo[2.1.1]hexane-1-carboxylic acid
  • 4-bromo-2-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanamido]benzoic acid
  • 2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,3-dimethylbutanamido]cyclopentane-1-carboxylic acid
  • 1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,3-dimethylbutanamido]cyclopentane-1-carboxylic acid
  • 2-(1-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopropanecarbonyl}-4-methylpyrrolidin-3-yl)acetic acid
  • 1-benzyl-4-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]piperidine-4-carboxylic acid
  • 4-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxybutanamido]cyclopent-1-ene-1-carboxylic acid
  • 2-{N-benzyl-1-[6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-7,7-dimethyl-2-oxabicyclo[3.2.0]heptan-6-yl]formamido}acetic acid
  • 2-{N-benzyl-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2,3-trimethylcyclohexyl]formamido}acetic acid
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