Loratadine Impurity 18

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Names

[ CAS No. ]:
31255-57-9

[ Name ]:
Loratadine Impurity 18

[Synonym ]:
MFCD02942420
3-[2-(3-Chlorophenyl)ethyl]-2-pyridinecarbonitrile
Loratadine Impurity 18

Chemical & Physical Properties

[ Density]:
1.23 g/cm3

[ Boiling Point ]:
375.7ºC at 760 mmHg

[ Melting Point ]:
71-72ºC

[ Molecular Formula ]:
C14H11ClN2

[ Molecular Weight ]:
242.70400

[ Flash Point ]:
181ºC

[ Exact Mass ]:
242.06100

[ PSA ]:
36.68000

[ LogP ]:
3.39188

[ Index of Refraction ]:
1.605

[ Storage condition ]:
Refrigerator

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-(3-CHLOROPHENYLETHYL)PYRIDINE N-OXIDE
  • Sodium cyanide
  • 3-[2-(3-CHLORO-PHENYL)-ETHYL]-PYRIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE
  • N-tert-butyl-3-methylpyridine-2-carboxamide
  • m-Chlorbenzyl chloride
  • 2-Cyano-3-methylpyridine

DownStream

  • Loratadine Impurity 2
  • N-Methyl Desloratadine
  • Loratadine
  • Desloratadine
  • (3-(3-CHLOROPHENETHYL)PYRIDIN-2-YL)(1-METHYLPIPERIDIN-4-YL)METHANONE HYDROCHLORIDE
  • (1-Methyl-4-piperidinyl) {3[2-(3-chlorophenyl) ethyl ]2-pyridinyl} methanone
  • Sch 37370

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • Desloratadine Impurity 18
  • Loratadine Impurity 3
  • Loratadine Impurity I
  • Loratadine Impurity 8
  • Loratadine Impurity 1
  • Loratadine Impurity 16
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2,6-Bis(1-methylethyl)-4-(4-methylphenoxy)benzenamine
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • N-(sec-butyl)-2-(2-(3,4-dimethylphenyl)-1,1-dioxido-3-oxo-2H-benzo[e][1,2,4]thiadiazin-4(3H)-yl)acetamide
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • {[3-(Tert-butyl)-4-methoxyphenyl]sulfonyl}(4-bromo-2-methylphenyl)amine
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde