RS-1

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Names

[ CAS No. ]:
312756-74-4

[ Name ]:
RS-1

[Synonym ]:
3-[(benzylamino)sulfonyl]-4-bromo-N-(4-bromophenyl)benzamide
RAD51-stimulatory compound 1
RS-1
4-BroMo-N-(4-broMophenyl)-3-[[(phenylMethyl)aMino]sulfonyl]benzaMide

Chemical & Physical Properties

[ Molecular Formula ]:
C20H16Br2N2O3S

[ Molecular Weight ]:
524.22600

[ Exact Mass ]:
521.92500

[ PSA ]:
83.65000

[ LogP ]:
6.48710

[ Storage condition ]:
-20℃

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency.

Nat. Commun. 7 , 10548, (2016)

Zinc-finger nuclease, transcription activator-like effector nuclease and CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR-associated protein 9) are becoming major tools ...

Nuclear domain 'knock-in' screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing.

Nucleic Acids Res. 43(19) , 9379-92, (2015)

CRISPR is a genome-editing platform that makes use of the bacterially-derived endonuclease Cas9 to introduce DNA double-strand breaks at precise locations in the genome using complementary guide RNAs....

A chemical compound that stimulates the human homologous recombination protein RAD51.

Proc. Natl. Acad. Sci. U. S. A. 105 , 15848-15853, (2008)

RAD51 and other members of the RecA family of strand exchange proteins assemble on ssDNA to form presynaptic filaments, which carry out the central steps of homologous recombination. A microplate-base...


More Articles


Related Compounds

  • RS-1,2,4-trimethylpiperazine
  • RS-1,2-dithiolane-3-propanoic acid
  • RS-1-(N-benzyloxycarbonylamino)ethanephosphonic acid
  • RS-1-[4-(2-Methoxyphenyl)-1-piperazinyl]-3-(1-naphthoxy)-2-propanol
  • RS-1-[4-(2-Methoxyphenyl)-1-piperazinyl]-3-(1-naphthoxy)-2-propanol
  • RS-1-methyl-2-(2,2-dimethyl-1,2-dioxolanyl)-2-p-tolylsulfinyl-1-ethanone
  • [3-(dimethylamino)propyl][(1-ethyl-3-methyl-1H-pyrazol-4-yl)methyl]amine
  • [(1-ethyl-3-methyl-1H-pyrazol-4-yl)methyl](heptyl)amine
  • [2-(diethylamino)ethyl][(1-ethyl-3-methyl-1H-pyrazol-4-yl)methyl]amine
  • [(1-ethyl-3-methyl-1H-pyrazol-4-yl)methyl][3-(propan-2-yloxy)propyl]amine
  • [3-(diethylamino)propyl][(1-ethyl-3-methyl-1H-pyrazol-4-yl)methyl]amine
  • [(1-ethyl-3-methyl-1H-pyrazol-4-yl)methyl][3-(morpholin-4-yl)propyl]amine
  • {[1-(difluoromethyl)-1H-pyrazol-5-yl]methyl}(2-methoxyethyl)amine
  • {[1-(difluoromethyl)-1H-pyrazol-5-yl]methyl}[2-(dimethylamino)ethyl]amine
  • 4-({[1-(difluoromethyl)-1H-pyrazol-5-yl]methyl}amino)butan-1-ol
  • {[1-(difluoromethyl)-1H-pyrazol-5-yl]methyl}(3-methoxypropyl)amine
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