Epibromohydrin

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Names

[ CAS No. ]:
3132-64-7

[ Name ]:
Epibromohydrin

[Synonym ]:
1-Bromo-2,3-epoxypropane
EINECS 221-525-3
2-Bromomethyl
2-bromomethyloxiran
Epibromohydrine
2-(Bromomethyl)oxirane
epibromhidrina
Oxirane, 2-(bromomethyl)-
Epibromohydrin
1,2-epoxy-3-bromopropane
Glycidyl bromide
MFCD00005130
3-Bromopropylene Oxide
Epibromhydrin
UNII:8E89677I6B

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
135.0±15.0 °C at 760 mmHg

[ Melting Point ]:
−40 °C(lit.)

[ Molecular Formula ]:
C3H5BrO

[ Molecular Weight ]:
136.975

[ Flash Point ]:
56.1±0.0 °C

[ Exact Mass ]:
135.952377

[ PSA ]:
12.53000

[ LogP ]:
0.85

[ Vapour Pressure ]:
9.7±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.504

[ Stability ]:
Stable. Incompatible with acids, bases, oxidizing agents, many of the more active metals.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TX4115000
CHEMICAL NAME :
Propane, 3-bromo-1,2-epoxy-
CAS REGISTRY NUMBER :
3132-64-7
BEILSTEIN REFERENCE NO. :
0079786
LAST UPDATED :
199710
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C3-H5-Br-O
MOLECULAR WEIGHT :
136.99
WISWESSER LINE NOTATION :
T3OTJ B1E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
50 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 249,55,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6241 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS07, GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H302-H315-H319-H335-H351

[ Precautionary Statements ]:
P261-P281-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R23/24/25;R34

[ Safety Phrases ]:
S26-S36/37

[ RIDADR ]:
UN 2558 6.1/PG 1

[ WGK Germany ]:
2

[ RTECS ]:
TX4115000

[ Packaging Group ]:
I

[ Hazard Class ]:
6.1(a)

[ HS Code ]:
2910900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Propanol,2,3-dibromo-, 1-acetate
  • Epichlorohydrin
  • allyl bromide
  • 1,3-Dibromo-2-propanol
  • 2,3-Dibromo-1-propanol
  • Glycerol

DownStream

  • 4-(oxiran-2-ylmethoxy)spiro[1,3-benzodioxole-2,1'-cyclohexane]
  • 2,3-Dihydro-1,4-benzodioxin-2-ylmethanol
  • 4-(2-OXIRANYLMETHOXY)BENZENECARBONITRILE
  • 5-Nitro-2-(oxiranylmethoxy)acetophenone
  • Benzophenone
  • Benzoic acid,2-propen-1-yl ester
  • Benzoin
  • 3-BROMO-1,2-PROPANEDIOL
  • [[p-(2-methoxyethyl)phenoxy]methyl]oxirane
  • (R)-3-BROMOPROPANE-1,2-DIOL

Customs

[ HS Code ]: 2910900090

[ Summary ]:
2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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Related Compounds

  • epibromohydrin
  • Epibromohydrin
  • (+)-Epibromohydrin
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 4-(chloromethyl)-1-((2,3-dihydrobenzofuran-5-yl)methyl)-1H-1,2,3-triazole
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • N-(2-(4-(isobutylamino)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-1-naphthamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 4-ethoxy-N-(4-((4-(ethylamino)-6-methylpyrimidin-2-yl)amino)phenyl)benzenesulfonamide