3-Bromobenzaldehyde

Suppliers

Names

[ Name ]:
3-Bromobenzaldehyde

[Synonym ]:
3-Bromobenzaldehyde
Benzaldehyde, m-bromo-
meta-bromobenzaldehyde
benzaldehyde,3-bromo
3-Formylbromobenzene
Benzaldehyde, 3-bromo-
3-bromo-benzaldehyd
m-bromo-benzaldehyd
3-BroMobenzeldehyde
3-bromophenylaldehyde
3-bromo-benzaldehyde
EINECS 221-526-9
MFCD00003345
m-Br-benzaldehyde
m-Bromobenzaldehyde

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
235.3±13.0 °C at 760 mmHg

[ Melting Point ]:
18-21 °C(lit.)

[ Molecular Formula ]:
C₇H₅BrO

[ Molecular Weight ]:
185.018

[ Flash Point ]:
96.1±0.0 °C

[ Exact Mass ]:
183.952377

[ PSA ]:
17.07000

[ LogP ]:
2.51

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.611

[ Water Solubility ]:
DECOMPOSES

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CU4820000

CHEMICAL NAME :: Benzaldehyde, 3-bromo-

CAS REGISTRY NUMBER :: 3132-99-8

LAST UPDATED :: 199806

DATA ITEMS CITED :: 4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534391 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1126 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - chromodacryorrhea Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534389

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534390

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
2810

[ WGK Germany ]:
3

[ RTECS ]:
CU4820000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
29130000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-(3-Bromophenyl)-1,3-dioxolane
3-Bromobenzyl alcohol
2-(3-bromophenyl)-1,3-dithiane
1,3-Dibromobenzene
Butylmagnesium chloride
(3-GLYCIDOXYPROPYL)METHYLDIETHOXYSILANE
3-Bromobenzyl bromide
1-Bromo-3-diethoxymethyl-benzene
3-Bromotoluene
3-Bromobenzoyl chloride

DownStream

3-(4-BROMOPHENYL)-2-PROPEN-1-OL
ethyl 3-(3-formylphenyl)prop-2-enoate
3-(3-Bromophenyl)propanoic acid
3-BROMOMANDELICACID
3-Phenoxybenzaldehyde
4-(3-Bromobenzyl)morpholine
3-FORMYL-BENZOIC ACID ETHYL ESTER
5-Bromoisoquinoline
7-Bromoisoquinoline
8-Bromoisoquinoline

Customs

[ HS Code ]: 2913000090

[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

Articles

A structure-activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities.

Bioorg. Med. Chem. 23 , 7543-64, (2015)

Inhibition of the enzymatic activity of histone deacetylase (HDAC) is a promising therapeutic strategy for cancer treatment and several distinct small molecule histone deacetylase inhibitors (HDACi) h...

[Determination of 3-bromobenzaldehyde, 3-phenoxybenzaldehyde and 3-phenoxybenzyl alcohol in the air of the work place].

Gig. Sanit. (2) , 69, (1990)

Relationship between metabolism and radioprotective activity of 2-phenylthiazolidine and its m-bromo derivative.

J. Med. Chem. 26(9) , 1317-9, (1983)

Molecular biotransformation of 2-phenylthiazolidine (1) and its m-bromo derivative (2) in the mouse is followed by autoradiographic studies and assessed by analysis of urinary metabolites. Cysteamine ...