Bromacil
Suppliers
Names
[ CAS No. ]:
314-40-9
[ Name ]:
Bromacil
[Synonym ]:
5-Bromo-3-(sec-butyl)-6-methylpyrimidine-2,4(1H,3H)-dione
5-bromo-3-(butan-2-yl)-6-methylpyrimidine-2,4(1H,3H)-dione
Uragon
2,4(1H,3H)-Pyrimidinedione, 5-bromo-6-methyl-3-(1-methylpropyl)-
Urox B
hibor
EINECS 206-245-1
5-Br
5-Brom-3-(butan-2-yl)-6-methylpyrimidin-2,4(1H,3H)-dion
5-Bromo-3-sec-butyl-6-methyl-2,4(1H,3H)-pyrimidinedione
(RS)-5-bromo-3-sec-butyl-6-methyluracil
Nalkil
Borea
5-bromo-6-methyl-3-(1-methylpropyl)-2,4(1H,3H)-pyrimidinedione
5-bromo-3-s-butyl-6-methyluracil
Rout
Bromax
5-Bromo-3-sec.-butyl-6-methyluracil
5-Brom-3-sec-butyl-6-methylpyrimidin-2,4(1H,3H)-dion
5-Bromo-3-sec-butyl-6-methyluracil
5-Bromo-3-sec-butyl-6-methylpyrimidine-2,4(1H,3H)-dione
rac-(3R)-5-bromo-3-(butan-2-yl)-6-methylpyrimidine-2,4(1H,3H)-dione
T6MVNVJ CY2&1 EE F1
MFCD00055364
Bromacil
Hyvar
5-bromo-6-methyl-3-(1-methylpropyl)pyrimidine-2,4(1H,3H)-dione
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
411ºC
[ Melting Point ]:
157-160°C
[ Molecular Formula ]:
C9H13BrN2O2
[ Molecular Weight ]:
261.116
[ Exact Mass ]:
260.016022
[ PSA ]:
54.86000
[ LogP ]:
2.10
[ Index of Refraction ]:
1.541
[ Stability ]:
Stable. Incompatible with strong acids, strong oxidizing agents.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YQ9100000
- CHEMICAL NAME :
- Uracil, 5-bromo-3-sec-butyl-6-methyl-
- CAS REGISTRY NUMBER :
- 314-40-9
- BEILSTEIN REFERENCE NO. :
- 0647896
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 34
- MOLECULAR FORMULA :
- C9-H13-Br-N2-O2
- MOLECULAR WEIGHT :
- 261.15
- WISWESSER LINE NOTATION :
- T6MVNVJ CY2&1 EE F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 641 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4800 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3040 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10350 mg/kg/2W-I
- TOXIC EFFECTS :
- Behavioral - ataxia Gastrointestinal - changes in structure or function of salivary glands Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 45625 mg/kg/2Y-C
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- DOSE :
- 38 mg/m3/2H
- SEX/DURATION :
- female 7-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB84-138973 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 10 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 1 ppm (10 mg/m3) JAN 1993 OEL-BELGIUM:TWA 1 ppm (11 mg/m3) JAN 1993 OEL-DENMARK:TWA 5 mg/m3 JAN 1993 OEL-FINLAND:TWA 1 ppm (10 mg/m3);STEL 3 ppm (30 mg/m3) JAN 1993 OEL-FRANCE:TWA 1 ppm (10 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 1 ppm (10 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 1 ppm (10 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 1 ppm (10 mg/m3);STEL 2 ppm (20 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO BROMACIL-air:10H TWA 1 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80830 No. of Facilities: 362 (estimated) No. of Industries: 11 No. of Occupations: 5 No. of Employees: 1905 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80830 No. of Facilities: 755 (estimated) No. of Industries: 7 No. of Occupations: 6 No. of Employees: 4372 (estimated) No. of Female Employees: 63 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335-H400
[ Precautionary Statements ]:
P261-P273-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;N: Dangerous for the environment;
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
S26-S61
[ RIDADR ]:
UN3077 9/PG 3
[ RTECS ]:
YQ9100000
[ HS Code ]:
2933599014
Customs
[ HS Code ]: 2933599014
[ Summary ]:
2933599014 6-nitroso-7h-purine。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%
Articles
Environ. Toxicol. Chem. 29(1) , 201-11, (2010)
Vallisneria americana Michx. (tapegrass) is an ecologically important submersed, vascular aquatic plant that provides food and shelter for many aquatic and waterfowl species. This plant often occurs c...
J. Chromatogr. Sci. 38(5) , 211-8, (2000)
A high-performance liquid chromatography procedure or the determination of the herbicides simazine, propazine, bromacil, metoxuron, and hexazinone is elaborated. Stationary phases RP8 and RP18 and mix...
Chemosphere 75(3) , 381-8, (2009)
To test whether the dose-addition (DA) model can predict the combined toxicity of the mixtures of herbicides that coexisted with insecticide(s), we selected five herbicides (simetryn, prometon, bromac...