Orotidine

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Names

[ CAS No. ]:
314-50-1

[ Name ]:
Orotidine

[Synonym ]:
UNII:B350MC02GZ
3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,6-dioxopyrimidine-4-carboxylic acid
1,2,3,6-Tetrahydro-2,6-dioxo-3-b-D-ribofuranosyl-4-pyrimidinecarboxylic Acid
6-Carboxyuridin
3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-2,6-diketo-pyrimidine-4-carboxylic acid
Uridine-6-carboxylic acid
3-b-D-Ribofuranosylorotic Acid
Orotidine
Uridine, 6-carboxy-
Orotidine (Uridine-6-carboxylic acid)
6-Carboxyuridine
URIDIN-6-CARBOXYLIC ACID

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Melting Point ]:
200ºC

[ Molecular Formula ]:
C₁₀H₁₂N₂O₈

[ Molecular Weight ]:
288.211

[ Exact Mass ]:
288.059357

[ PSA ]:
162.08000

[ LogP ]:
-1.24

[ Index of Refraction ]:
1.678

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Pyrophosphate interactions at the transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.

J. Am. Chem. Soc. 132(25) , 8787-94, (2010)

Orotate phosphoribosyltransferases from Plasmodium falciparum and human sources (PfOPRT and HsOPRT) use orotidine as a slow substrate in the pyrophosphorolysis reaction. With orotidine, intrinsic kine...

The allopurinol load test lacks specificity for primary urea cycle defects but may indicate unrecognized mitochondrial disease.

J. Inherit. Metab. Dis. 22(2) , 174-84, (1999)

Thirty-three children ranging from 2 weeks to 12 years of age were selected for allopurinol loading, 16 on the basis of an increased urinary ourotate excretion detected by routine organic acid analysi...

Orotidine accumulation in human erythrocytes during allopurinol therapy: association with high urinary oxypurinol-7-riboside concentrations in renal failure and in the Lesch-Nyhan syndrome.

Clin. Sci. 80(3) , 191-7, (1991)

1. A compound identified as orotidine has been found in the erythrocytes of all subjects on allopurinol. 2. The erythrocyte orotidine concentrations were much higher in patients with renal failure or ...

orotidine 5'-phosphate
orotidine free acid approx.
arabino-2,2'-anhydro-orotidine
Orotidine 5′-monophosphate trisodium salt
arabino-2,2'-anhydro-orotidine methyl ester
orotidine-5'-monophosphate*decarboxylase purified fr
(1R,2S)-2-(1-phenyl-1H-pyrazol-4-yl)cyclopropan-1-amine hydrochloride
trans-2-(1-Methyl-1h-pyrazol-4-yl)cyclopropanamine dihydrochloride
2-Amino-3-(3,4-dihydroxy-2-methylphenyl)propanoic acid hydrobromide
7-Ethyl-[1,2,4]triazolo[4,3-c]pyrimidine-5-thiol
2,3-Dimethyl-1lambda4-thiomorpholin-1-one hydrochloride
3,5-difluoro-N-methylpyridin-2-amine hydrochloride
9-butyl-10-[(1E)-3-[(1E)-3-[(1E)-3-[(10E)-9-butyl-4-methyl-3-oxa-9-azatetracyclo[6.6.1.0^{2,6}.0^{11,15}]pentadeca-1,6,8(15),11,13-pentaen-10-ylidene]prop-1-en-1-yl]-5,5-dimethylcyclohex-2-en-1-ylidene]prop-1-en-1-yl]-4-methyl-3-oxa-9-azatetracyclo[6.6.1.0^{2,6}.0^{11,15}]pentadeca-1(15),2(6),7,9,11,13-hexaen-9-ium; tetrafluoroboranuide
(R)-4-(1-((tert-Butoxycarbonyl)amino)ethyl)benzoic acid hydrochloride
rac-(1R,2S,6r,7S)-10-Oxa-4-azatricyclo[5.2.1.0~2,6~]decane hydrochloride
Bicyclo[4.2.0]octa-1,3,5-trien-3-amine hydrochloride

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