IU1

Suppliers

Names

[ Name ]:
IU1

[Synonym ]:
Ethanone, 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-
IU1
F1142-1244
1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone
Usp14 inhibitor

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
437.0±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₁FN₂O

[ Molecular Weight ]:
300.371

[ Flash Point ]:
218.1±28.7 °C

[ Exact Mass ]:
300.163788

[ PSA ]:
25.24000

[ LogP ]:
4.07

[ Appearance of Characters ]:
off-white to light brown

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.585

[ Storage condition ]:
Store at +4°C

[ Water Solubility ]:
DMSO: >10mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
41

[ Safety Phrases ]:
61

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Post-endocytotic Deubiquitination and Degradation of the Metabotropic γ-Aminobutyric Acid Receptor by the Ubiquitin-specific Protease 14.

J. Biol. Chem. 291 , 7156-70, (2016)

Mechanisms controlling the metabotropic γ-aminobutyric acid receptor (GABAB) cell surface stability are still poorly understood. In contrast with many other G protein-coupled receptors (GPCR), it is n...

Ubiquitin-specific protease 14 modulates degradation of cellular prion protein.

Sci. Rep. 5 , 11028, (2015)

Prion diseases are fatal neurodegenerative disorders characterized by the accumulation of prion protein (PrP(C)). To date, there is no effective treatment for the disease. The accumulated PrP, termed ...

IU1