thiophosphoric acid o,o'-diethyl ester-s-(2-dimethylamino-ethyl ester)

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Names

[ CAS No. ]:
3147-20-4

[ Name ]:
thiophosphoric acid o,o'-diethyl ester-s-(2-dimethylamino-ethyl ester)

[Synonym ]:
Thiophosphorsaeure-O,O'-diaethylester-S-(2-dimethylamino-aethylester)
Phosphorothioic acid,S-(2-(dimethylamino)ethyl) o,o-diethyl ester,ethanedioate (1:1)
Monothiophosphorsaeure-O.O-diethyl-S-<2-dimethylamino-ethyl>-ester
S-(2-(N,N-Dimethylamino)ethyl)o,o-diethyl phosphorothiolate
217Ao
Echothiophat
Phosphorothioic acid,o,o-diethyl S-(2-dimethylaminoethyl) ester
O,O-diethyl S-(2-dimethylaminoethyl) thiophosphate
2-Diaethylphosphinomercapto-aethyl-dimethyl-amin

Chemical & Physical Properties

[ Density]:
1.103g/cm3

[ Boiling Point ]:
280.6ºC at 760 mmHg

[ Molecular Formula ]:
C8H20NO3PS

[ Molecular Weight ]:
241.28800

[ Flash Point ]:
123.5ºC

[ Exact Mass ]:
241.09000

[ PSA ]:
73.88000

[ LogP ]:
2.46230

[ Index of Refraction ]:
1.471

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TF1665000
CHEMICAL NAME :
Phosphorothioic acid, O,O-diethyl S-(2-dimethylaminoethyl) ester
CAS REGISTRY NUMBER :
3147-20-4
BEILSTEIN REFERENCE NO. :
1780326
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H20-N-O3-P-S
MOLECULAR WEIGHT :
241.32
WISWESSER LINE NOTATION :
2OPO&O2&S2N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2455 ug/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage)
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 35,806,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
230 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 19,810,1976

Safety Information

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • sodium 2-(dimethylamino)ethanethiolate
  • Diethyl chlorophosphate
  • 2-(Dimethylamino)ethanol
  • 2-(DIMETHYLAMINO)ETHANETHIOL
  • ethene
  • Triethyl phosphite

DownStream

  • Echothiophate Iodide

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 1-Piperidinecarboxylic acid, 4-[[3-[(5-amino-2-pyridinyl)oxy]phenyl]methylene]-, 1,1-dimethylethyl ester
  • 4-{2-azabicyclo[3.1.0]hexan-2-yl}-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-oxobutanoic acid
  • 5-[(3aR,6aS)-5-methyl-octahydropyrrolo[3,4-c]pyrrol-2-yl]-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-oxopentanoic acid
  • 4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-[3-(2-methoxyethoxy)azetidin-1-yl]-5-oxopentanoic acid
  • (4S)-2-(2,6-dichlorophenyl)-3-{[(9H-fluoren-9-yl)methoxy]carbonyl}-1,3-thiazolidine-4-carboxylic acid
  • 1-{1-[(Tert-butoxy)carbonyl]-3-hydroxyazetidin-3-yl}cycloheptane-1-carboxylic acid
  • 9H-fluoren-9-ylmethyl 5-amino-8-fluoro-7-methyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate
  • tert-butyl N-[8-(ethylamino)-7-methylisoquinolin-5-yl]carbamate
  • 9H-fluoren-9-ylmethyl N-[(2-{[(propan-2-yl)amino]methyl}thiophen-3-yl)methyl]carbamate
  • 1-[(Tert-butoxy)carbonyl]-3-(1-hydroxycyclohexyl)azetidine-3-carboxylic acid
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