PAC-1

Suppliers

Names

[ Name ]:
PAC-1

[Synonym ]:
1-Piperazineacetic acid, 4-(phenylmethyl)-, 2-[(1Z)-[2-hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide
N'-[(Z)-(3-Allyl-2-hydroxyphenyl)methylene]-2-(4-benzyl-1-piperazinyl)acetohydrazide
(4-Benzylpiperazino)acetic acid (3-allyl-2-hyroxybenzylidene)hydrazide 1-Piperazineacetic acid
PAC-1
N'-[(Z)-(3-Allyl-2-hydroxyphenyl)methylene]-2-(4-benzylpiperazin-1-yl)acetohydrazide
PAC1
PAC-1,PAC1
(E)-N'-(3-allyl-2-hydroxybenzylidene)-2-(4-benzylpiperazin-1-yl)acetohydrazide
PAC 1

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Molecular Formula ]:
C₂₃H₂₈N₄O₂

[ Molecular Weight ]:
392.494

[ Exact Mass ]:
392.221222

[ PSA ]:
68.17000

[ LogP ]:
4.26

[ Appearance of Characters ]:
white

[ Index of Refraction ]:
1.597

[ Storage condition ]:
Store at +4°C

[ Water Solubility ]:
DMSO: ≥10mg/mL

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335-H400

[ Precautionary Statements ]:
P261-P273-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn,N

[ Risk Phrases ]:
22-36/37/38-50/53

[ Safety Phrases ]:
26-36/37-60-61

[ RIDADR ]:
UN 3077

Precursor & DownStream

Precursor

Salicylaldehyde, 3-allyl-
2-(4-Benzylpiperazin-1-yl)acetohydrazid

DownStream

Articles

DL-3-n-butylphthalide inhibits platelet activation via inhibition of cPLA2-mediated TXA2 synthesis and phosphodiesterase.

Platelets 26 , 736-44, (2015)

Aberrant platelet activation plays a critical role in the pathogenesis of heart attack and stroke. DL-3-n-butylphthalide (NBP) has been approved in China to treat stroke with multiple mechanisms. The ...

HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi.

Thromb. Haemost. 114 , 994-1003, (2015)

High mobility group box 1 (HMGB1) acts as both a nuclear protein that regulates gene expression, as well as a pro-inflammatory alarmin that is released from necrotic or activated cells. Recently, HMGB...

Detection of HIT antibody dependent platelet aggregation using novel surface imprinting approach.

Talanta 147 , 1-7, (2015)

We present a fast, robust and straightforward spin force assisted surface imprinting approach for activated platelets and demonstrate that Heparin induced thrombocytopenia (HIT) platelet aggregation c...

(S)-phenylacetylcarbinol
1-hydroxy-1-phenylacetone
2-[1-(2-hydroxy-3,5-dimethylphenyl)cyclohexyl]-4,6-dimethylphenol
3-[1-(2,5-dimethylthiophen-3-yl)octadecyl]-4-propan-2-ylideneoxolane-2,5-dione
hex-1-enyl(diphenyl)phosphane
3-(1-aminophenothiazin-10-ium-10-ylidene)phenothiazin-1-amine
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-l-phenylalanine ethyl ester
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
2H-Benzimidazol-2-one, 6-chloro-1-(3-chloropropyl)-1,3-dihydro-, hydrochloride
(4-Methyl-tetrahydro-furan-2-yl)-methanol
7,7-Difluoro-4-methylbicyclo[4.1.0]heptane-3-carboxylic acid
4-(1-Aminocyclopentyl)-2-bromo-6-methoxyphenol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide