eIF4E/eIF4G Interaction Inhibitor, 4EGI-1

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Names

[ CAS No. ]:
315706-13-9

[ Name ]:
eIF4E/eIF4G Interaction Inhibitor, 4EGI-1

[Synonym ]:
(2Z)-2-{[4-(3,4-Dichlorophenyl)-4,5-dihydro-1,3-thiazol-2-yl]hydrazono}-3-[2-(dihydroxyamino)phenyl]propanoic acid
eIF4E/eIF4G Interaction Inhibitor,4EGI-1
Benzenepropanoic acid, α-[2-[4-(3,4-dichlorophenyl)-4,5-dihydro-2-thiazolyl]hydrazinylidene]-2-(dihydroxyamino)-, (αZ)-
4EGI-1

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
712.2±70.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H12Cl2N4O4S

[ Molecular Weight ]:
451.28

[ Flash Point ]:
384.5±35.7 °C

[ PSA ]:
143.05000

[ LogP ]:
2.46

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.714

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-(3,4-Dichlorophenyl)-2-hydrazino-1,3-thiazole
  • 2-Nitrophenylpyruvic acid

DownStream

Related Compounds

  • B7/CD28 interaction inhibitor 1
  • SORT-PGRN interaction inhibitor 1
  • HIV-1 Integrase Inhibitor 1
  • Type II topoisomerase inhibitor 1
  • Viral 2C protein inhibitor 1
  • INCB053914 phosphate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 1,3,5,6-Tetramethyl-4-(prop-2-enoyl)piperazin-2-one
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide