Prostaglandin A2 methyl ester

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Names

[ CAS No. ]:
31753-19-2

[ Name ]:
Prostaglandin A2 methyl ester

[Synonym ]:
PGA2-methylester
Prosta-5,10,13-trien-1-oic acid, 15-hydroxy-9-oxo-, methyl ester, (5Z,13E,15S)-
Prostaglandin A2 methyl ester
Methyl (5Z,13E,15S)-15-hydroxy-9-oxoprosta-5,10,13-trien-1-oate

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
477.4±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H32O4

[ Molecular Weight ]:
348.476

[ Flash Point ]:
157.9±22.2 °C

[ Exact Mass ]:
348.230072

[ PSA ]:
63.60000

[ LogP ]:
3.80

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.534

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • PROSTAGLANDIN A2
  • methyl iodide
  • Methyl (5Z,13E,8R,11R,12R,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(anti-oximino)-5,13-prostadienoate
  • Methyl (5Z,13E,8R,9S,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(methylamino)-8-(phenylsulfonyl)-5,13-prostadienoate
  • methyl (E)-7-[1-(benzenesulfonyl)-5-dimethylamino-3-(dimethyl-tert-butyl-silyl)oxy-2-[(E)-3-(dimethyl-tert-butyl-silyl)oxyoct-1-enyl]cyclopentyl]hept-5-enoate
  • Methyl (5Z,13E,8R,9S,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-[[carbo(2',2',2'-trichloroethoxy)]methylamino]-8-(phenylsulfonyl)-5,13-prostadienoate
  • Methyl (5Z,13E,8R,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(anti-oximino)-8-(phenylsulfonyl)-5,13-prostadienoate
  • diazomethane

DownStream

  • tromethamine
  • Prostaglandin F2α methyl ester
  • Prostaglandin B2

Related Compounds

  • 15(S)-acetate Prostaglandin A2 methyl ester
  • 16,16-dimethylprostaglandin A2 methyl ester
  • Prostaglandin A2 methyl ester 15-t-butyldimethylsilyl ether
  • prostaglandin A2 isopropyl ester
  • Prostaglandin D2 methyl ester
  • Prostaglandin A1 methyl ester
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (5-Hydroxyadamantan-2-yl)carbamic acid tert-butyl ester
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • Methyl 2-((4-chlorophenyl)ethynyl)pyrimidine-5-carboxylate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine