4-Fluorophthalic anhydride

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Names

[ CAS No. ]:
319-03-9

[ Name ]:
4-Fluorophthalic anhydride

[Synonym ]:
4-Fluor-phthalsaeure-anhydrid
4-Fluorophthalic anhydride
5-Fluoroisobenzofuran-1,3-dione
4-FLUOROPHTHALIC ACID ANHYDRIDE
4-Fluorophthalicanhydride
1,3-Isobenzofurandione, 5-fluoro-
4-FPA
5-Fluoro-1,3-isobenzofurandione
5-fluoro-isobenzofuran-1,3-dione
4-fluorophthalic ahydride
4-Fluorophthalic
MFCD00191363
5-Fluoro-2-benzofuran-1,3-dione
5-fluoro-3-isobenzofurandione

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
304.1±25.0 °C at 760 mmHg

[ Melting Point ]:
75-79 °C(lit.)

[ Molecular Formula ]:
C8H3FO3

[ Molecular Weight ]:
166.11

[ Flash Point ]:
133.3±18.1 °C

[ Exact Mass ]:
166.006622

[ PSA ]:
43.37000

[ LogP ]:
1.65

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.583

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H319-H335

[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38;R42/43

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
2

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Nitrophthalic anhydride
  • diethyl 4-fluorobenzene-1,2-dicarboxylate
  • 4-Chlorophtalic anhydride
  • 4-Fluorophthalic acid

DownStream

  • 4,4'-(4,4'-Isopropylidenediphenoxy)diphthalic Anhydride
  • 6-Fluoroindoline
  • 5,5'-Oxybis(isobenzofuran-1,3-dione)
  • 5-fluoro-2-(4-nitrophenyl)isoindole-1,3-dione
  • 1,2-Benzenedimethanol,4-fluoro-
  • 1,2-Bis(bromomethyl)-4-fluorobenzene

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis and biological characterisation of 18F-SIG343 and 18F-SIG353, novel and high selectivity σ2 radiotracers, for tumour imaging properties.

EJNMMI Res. 3 , 80, (2013)

Sigma2 (σ2) receptors are highly expressed in cancer cell lines and in tumours. Two novel selective 18F-phthalimido σ2 ligands, 18F-SIG343 and 18F-SIG353, were prepared and characterised for their pot...


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Related Compounds

  • 4-Fluorophthalic acid
  • methyl 2,2,3,3-tetrafluoropropanoate
  • 3-Bromo-4-fluorophthalic acid
  • N-(1-octylnonyl)-perylene-3,4:9,10-tetracarboxylic acid-3,4-anhydride-9,10-carboximide
  • Dimethyl 4-fluorophthalate
  • 4-METHYLPENTANOIC ANHYDRIDE
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 9-(3-Aminopropyl)-1-oxa-9-azaspiro[5.5]undecan-4-ol
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide