Z-Pyr-OH

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Names

[ CAS No. ]:
32159-21-0

[ Name ]:
Z-Pyr-OH

[Synonym ]:
1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(phenylmethyl) ester, (S)-
(S)-1-(benzyloxycarbonyl)-5-oxopyrrolidine-2-carboxylic acid
(S)-5-Oxo-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester
MFCD00037352
cbz-L-Pyroglutamic Acid
N-carbobenzoxy-L-pyroglutamic acid
(S)-L-(Benzyloxycarbonyl)-5-Oxopyrrolidine-2-Carboxylic Acid
Z-L-pGlu-OH
N-Cbz-5-oxo-L-proline
EINECS 250-936-0
Z-L-pyroglutamic acid
Z-Pyr-OH
benzyloxycarbonyl-L-pyroglutamic acid
(2S)-5-oxo-1-[benzyloxycarbonyl]pyrrolidine-2-carboxylic acid
1-[(Benzyloxy)carbonyl]-5-oxo-L-proline
N2-(benzyloxycarbonyl)-L-pyroglutamic acid
AmbotzZAA1244
(S)-1-Benzyloxycarbonyl-5-oxopyrrolidine-2-carboxylic acid
1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(phenylmethyl) ester, (2S)-

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
525.4±50.0 °C at 760 mmHg

[ Melting Point ]:
128-130°C

[ Molecular Formula ]:
C13H13NO5

[ Molecular Weight ]:
263.246

[ Flash Point ]:
271.5±30.1 °C

[ Exact Mass ]:
263.079376

[ PSA ]:
83.91000

[ LogP ]:
-0.35

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.597

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933790090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • sodium carbonate
  • Benzyl chloroformate
  • L-Pyroglutamicacid
  • benzyl N-(2,6-dioxooxan-3-yl)carbamate
  • Z-Glu-OH

DownStream

  • L-Pro-ol
  • Z-Glu-OtBu
  • (S)-tert-Butyl 2-(benzyloxycarbonylamino)-5-hydroxypentanoate
  • 1-Benzyl 2-methyl (2S)-5-oxo-1,2-pyrrolidinedicarboxylate

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Articles

Inactivation of pyroglutamyl aminopeptidase by N alpha-carbobenzoxy-L-pyroglutamyl chloromethyl ketone.

J. Biochem. 90(2) , 433-7, (1981)

Pyroglutamyl aminopeptidase [pyrrolidone-carboxylate peptidase: EC 3.4.11.8] from Bacillus amyloliquefaciens was inactivated rapidly and irreversibly by N alpha-carbobenzoxy-L-pyroglutamyl chloromethy...


More Articles

Related Compounds

  • Z-Pyr-Osu
  • Z-Pyr-Ala-Lys(Z)-Ser-OMe
  • Z-Pyr-Ala-Lys(Z)-Ser-NHNH2
  • boc-pyr-oh dcha
  • Boc-Pyr-OH
  • (R)-1-((Benzyloxy)carbonyl)-5-oxopyrrolidine-2-carboxylic acid
  • 2-{1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanoyl]pyrrolidin-3-yl}acetic acid
  • (2R)-2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1,3-thiazol-5-yl]formamido}-3-methylbutanoic acid
  • 3-[(3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)heptanamido]-2-hydroxypropanoic acid
  • 2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexyl]-N-(2-hydroxyethyl)acetamido}acetic acid
  • 4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,3-dimethylbutanamido]but-2-enoic acid
  • 6-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]acetamido}-4-methylhexanoic acid
  • 1-Chloro-5-(propan-2-yl)isoquinoline-3-carboxylic acid
  • 7-Bromo-2-(difluoromethyl)-4-ethylquinoline
  • 6-Bromo-4-ethyl-2-(propan-2-yl)quinoline
  • 7-chloro-1-oxo-3,4-dihydro-1H-2-benzopyran-3-carbaldehyde
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