2-Amino-3-hydroxy-2'-(2,3,4-trihydroxybenzyl)propionohydrazide

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Names

[ CAS No. ]:
322-35-0

[ Name ]:
2-Amino-3-hydroxy-2'-(2,3,4-trihydroxybenzyl)propionohydrazide

[Synonym ]:
bensarazide
Benseraszide
Ro 4-4602
Benserazida
DL-Seryltrihydroxybenzylhydrazine
MFCD00242633
2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide
Serazide
Benserazidum

Chemical & Physical Properties

[ Density]:
1.541 g/cm3

[ Boiling Point ]:
574.2ºC at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₅N₃O₅

[ Molecular Weight ]:
257.24300

[ Flash Point ]:
301ºC

[ Exact Mass ]:
257.10100

[ PSA ]:
148.07000

[ Index of Refraction ]:
1.678

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VT9632200

CHEMICAL NAME :: Serine, 2-(2,3,4-trihydroxybenzyl)hyrazide, DL-

CAS REGISTRY NUMBER :: 322-35-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H15-N3-O5

MOLECULAR WEIGHT :: 257.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 23400 mg/kg/90D-C

TOXIC EFFECTS :: Behavioral - ataxia Kidney, Ureter, Bladder - other changes in urine composition Musculoskeletal - other changes

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 66,201,1982 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2880 mg/kg

SEX/DURATION :: female 90 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 66,201,1982

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ HS Code ]:
2928000090

Customs

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Related Compounds

2-{[(Oxolan-2-yl)methyl]amino}-1,3-thiazole-4-carboxylic acid
2'-Isobutyl-1'-oxo-1',4'-dihydro-2'H-spiro[cyclopentane-1,3'-isoquinoline]-4'-carboxylic acid
1-[Cyano(thiophen-2-yl)methyl]piperidine-4-carboxylicacid
1-Amino-3-(thiophene-2-sulfonyl)propan-2-ol
3-Ethyl-2-oxo-1,2-dihydroquinoline-6-sulfonyl chloride
3-Methyl-6-phenylimidazo[2,1-b][1,3]thiazol-5-amine
7-Cyclopropyl-2-methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid
2,7-Dicyclopropylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid
5-[(1-Bromopropan-2-yl)oxy]-1,2,3,4-tetrahydronaphthalene
N-(2-hydroxy-2-(thiophen-2-yl)ethyl)furan-2-carboxamide

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