(-)-Corey lactone diol

Suppliers

Names

[ Name ]:
(-)-Corey lactone diol

[Synonym ]:
(-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one
(-)-Corey lactone
(-)-CoreyLactoneDiol
2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-(hydroxymethyl)-, (3aR,4S,5R,6aS)-
MFCD00075234
(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one
(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
406.6±25.0 °C at 760 mmHg

[ Melting Point ]:
117-119 °C(lit.)

[ Molecular Formula ]:
C₈H₁₂O₄

[ Molecular Weight ]:
172.178

[ Flash Point ]:
172.9±16.7 °C

[ Exact Mass ]:
172.073563

[ PSA ]:
66.76000

[ LogP ]:
-2.18

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.546

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R24/25

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(-)-Corey lactone benzoate
((3aR,4S,6aS)-5-acetoxy-2-oxohexahydro-2H-cyclopenta[b]furan-4-yl)Methyl acetate
(3aR,4S,5R,6aS)-4-((tert-butyldimethylsilyloxy)methyl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one
(3aR,4S,5R,6aS)-4-[(Acetyloxy)methyl]hexahydro-5-hydroxy-2H-cyclopenta[b]furan-2-one
[(3aR,4S,5R,6aS)-4-(hydroxymethyl)-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] acetate
(4aS,4bR,7aS,8aR)-hexahydrofuro[3',2':3,4]cyclopenta[1,2-d][1,3]dioxin-6(7aH)-one
(-)-Corey lactone 4-phenylbenzoate alcohol

DownStream

Lubiprostone
(+)-Cloprostenol
LatanoprostAcid
Latanoprost Lactol
Latanoprost
(3AR,4S,5R,6AS)-4-(((TERT-BUTYLDIMETHYLSILYL)OXY)METHYL)-5-((TETRAHYDRO-2H-PYRAN-2-YL)OXY)HEXAHYDRO-2H-CYCLOPENTA[B]FURAN-2-ONE
Sulprostone
tromethamine
(-)-3-OXO-6-BETA-TRITYLOXYMETHYL-7-ALPHA-BENZOYL-OXY-2-OXABICYCLO[3.3.0!OCTANE
Lubiprostone

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%