NPS-2143 hydrochloride

Suppliers

Names

[ Name ]:
NPS-2143 hydrochloride

[Synonym ]:
MFCD16038896
Benzonitrile, 2-chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]-, hydrochloride (1:1)
2-Chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(2-naphthyl)-2-propanyl]amino}propoxy]benzonitrile hydrochloride (1:1)
NPS-2143 (hydrochloride)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₆Cl₂N₂O₂

[ Molecular Weight ]:
445.381

[ Exact Mass ]:
444.137146

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H410

[ Precautionary Statements ]:
P273-P280-P501

[ Hazard Codes ]:
Xn,N

[ Risk Phrases ]:
20/21/22-50/53

[ Safety Phrases ]:
36/37-60-61

[ RIDADR ]:
UN 3077 9 / PGIII

Articles

Acetylcholine protects mesenteric arteries against hypoxia/reoxygenation injury via inhibiting calcium-sensing receptor.

J. Pharmacol. Sci. 127 , 481-8, (2015)

The Ca(2+)-sensing receptor (CaSR) plays an important role in regulating vascular tone. In the present study, we investigated the positive effects of the vagal neurotransmitter acetylcholine by suppre...

Parathyroid-specific deletion of dicer-dependent microRNAs abrogates the response of the parathyroid to acute and chronic hypocalcemia and uremia.

FASEB J. 29 , 3964-76, (2015)

MicroRNAs (miRNAs) down-regulate gene expression and have vital roles in biology but their functions in the parathyroid are unexplored. To study this, we generated parathyroid-specific Dicer1 knockout...

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