NPS-2143 hydrochloride

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Names

[ CAS No. ]:
324523-20-8

[ Name ]:
NPS-2143 hydrochloride

[Synonym ]:
MFCD16038896
Benzonitrile, 2-chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]-, hydrochloride (1:1)
2-Chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(2-naphthyl)-2-propanyl]amino}propoxy]benzonitrile hydrochloride (1:1)
NPS-2143 (hydrochloride)

Chemical & Physical Properties

[ Molecular Formula ]:
C24H26Cl2N2O2

[ Molecular Weight ]:
445.381

[ Exact Mass ]:
444.137146

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H410

[ Precautionary Statements ]:
P273-P280-P501

[ Hazard Codes ]:
Xn,N

[ Risk Phrases ]:
20/21/22-50/53

[ Safety Phrases ]:
36/37-60-61

[ RIDADR ]:
UN 3077 9 / PGIII

Articles

Acetylcholine protects mesenteric arteries against hypoxia/reoxygenation injury via inhibiting calcium-sensing receptor.

J. Pharmacol. Sci. 127 , 481-8, (2015)

The Ca(2+)-sensing receptor (CaSR) plays an important role in regulating vascular tone. In the present study, we investigated the positive effects of the vagal neurotransmitter acetylcholine by suppre...

Parathyroid-specific deletion of dicer-dependent microRNAs abrogates the response of the parathyroid to acute and chronic hypocalcemia and uremia.

FASEB J. 29 , 3964-76, (2015)

MicroRNAs (miRNAs) down-regulate gene expression and have vital roles in biology but their functions in the parathyroid are unexplored. To study this, we generated parathyroid-specific Dicer1 knockout...


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Related Compounds

  • NPS-2143
  • NPS-Amino-acetonitril
  • Nps-Ala-ONSu
  • Nps-Gly-ONSu
  • nps 846
  • 6-FLUORONOREPINEPHRINE HYDROCHLORIDE (6- FNE HCL)
  • Methyl(2,4,4-trimethylhexan-2-yl)amine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide