2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid

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Names

[ CAS No. ]:
32675-71-1

[ Name ]:
2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid

[Synonym ]:
N-Phthalyl-L-tryptophan
RG108 &N-phthalimide l-tryptophane
(2S)-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid
RG108/RG-108
RG108/DNA Methyltransferase Inhibitor/N-Phthalyl-L-tryptophan
(S)-2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-3-(1H-indol-3-yl)propionic acid
DNA Methyltransferase Inhibitor
N-Phth-Trp-OH

Chemical & Physical Properties

[ Density]:
1.502g/cm3

[ Boiling Point ]:
606ºC at 760 mmHg

[ Molecular Formula ]:
C19H14N2O4

[ Molecular Weight ]:
334.32500

[ Flash Point ]:
320.3ºC

[ Exact Mass ]:
334.09500

[ PSA ]:
90.47000

[ LogP ]:
2.39770

[ Index of Refraction ]:
1.741

Safety Information

[ HS Code ]:
2925190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • L(-)-Tryptophan
  • 2,5-DIOXOPYRROLIDIN-1-YL METHYL PHTHALATE
  • N-carbethoxyphthalimide
  • (S)-(-)-tryptophan hydrochloride
  • Phthalic anhydride
  • Monomethyl phthalate

DownStream

  • 1H-Isoindole-1,3(2H)-dione,2-[2-(1H-indol-3-yl)ethyl]-

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Related Compounds

  • 1-[(3-Methylazetidin-3-yl)oxy]naphthalen-2-ol
  • 2-(3-Methoxy-4-methylphenyl)butanoic acid
  • 2-(1H-indol-5-yl)propanal
  • {1-[(1H-indazol-3-yl)methyl]cyclopropyl}methanamine
  • 3-[(6-Methoxypyridin-3-yl)oxy]propan-1-amine
  • 1-(6-methoxypyridin-3-yl)-N-methylcyclopropan-1-amine
  • 1-(2-methyl-2H-indazol-3-yl)cyclopropan-1-amine
  • 2-Amino-3-(4-fluoro-2-methoxyphenyl)propan-1-ol
  • 3-(2,2,3,3-Tetramethylcyclopropyl)butan-1-amine
  • [1-(3-Fluoro-4-nitrophenyl)-2,2-dimethylcyclopropyl]methanol
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