2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid

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Names

[ CAS No. ]:
32675-71-1

[ Name ]:
2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid

[Synonym ]:
N-Phthalyl-L-tryptophan
RG108 &N-phthalimide l-tryptophane
(2S)-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid
RG108/RG-108
RG108/DNA Methyltransferase Inhibitor/N-Phthalyl-L-tryptophan
(S)-2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-3-(1H-indol-3-yl)propionic acid
DNA Methyltransferase Inhibitor
N-Phth-Trp-OH

Chemical & Physical Properties

[ Density]:
1.502g/cm3

[ Boiling Point ]:
606ºC at 760 mmHg

[ Molecular Formula ]:
C19H14N2O4

[ Molecular Weight ]:
334.32500

[ Flash Point ]:
320.3ºC

[ Exact Mass ]:
334.09500

[ PSA ]:
90.47000

[ LogP ]:
2.39770

[ Index of Refraction ]:
1.741

Safety Information

[ HS Code ]:
2925190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • L(-)-Tryptophan
  • 2,5-DIOXOPYRROLIDIN-1-YL METHYL PHTHALATE
  • N-carbethoxyphthalimide
  • (S)-(-)-tryptophan hydrochloride
  • Phthalic anhydride
  • Monomethyl phthalate

DownStream

  • 1H-Isoindole-1,3(2H)-dione,2-[2-(1H-indol-3-yl)ethyl]-

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Related Compounds

  • CID 132398928
  • tert-butyl 2-[(Z)-N'-hydroxycarbamimidoyl]azetidine-1-carboxylate
  • [(2S,4S)-1-benzyl-4-methoxypyrrolidin-2-yl]methanamine
  • 2-(Benzyloxy)-6-(piperidin-4-yl)pyridine
  • Benzene, 1-bromo-3-(difluoromethyl)-2-fluoro-4-nitro-
  • 4-(Methoxyimino)-3-methyl-1H-pyrazol-5(4H)-one
  • 7-[3-(4-Piperidinyloxy)phenyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
  • (3-Amino-2,2-difluoropropyl)(methyl)(propan-2-yl)amine
  • 3-(3,5-Dimethylpiperidin-1-yl)-2,2-difluoropropan-1-amine
  • 2,2-Difluoro-3-(4-methyl-1,4-diazepan-1-yl)propan-1-amine
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