(2S,2αR)-4-benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]]ethoxy-morpholin-3-one

Names

[ CAS No. ]:
327623-36-9

[ Name ]:
(2S,2αR)-4-benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]]ethoxy-morpholin-3-one

[Synonym ]:
(2S,2AR)-4-BENZYL-2-[1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]]ETHOXY-MORPHOLIN-3-ONE
(S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-benzylmorpholin-3-one

Chemical & Physical Properties

[ Molecular Formula ]:
C21H19F6NO3

[ Molecular Weight ]:
447.37100

[ Exact Mass ]:
447.12700

[ PSA ]:
38.77000

[ LogP ]:
5.12480

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Benzyl-2,3-Morpholinedione

DownStream

  • (2R,3S)-2-[(1R)-1-[3,5-bis(Trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)morpholine
  • (2R)-4-benzyl-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]morpholin-3-one
  • Aprepitant