(2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

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Names

[ CAS No. ]:
327623-37-0

[ Name ]:
(2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

[Synonym ]:
(2R,3S)-2-{(1R)-1-[3,5-bis-trifluoromethylphenyl]ethoxy}-3-(4-fluorophenyl)morpholine
(2S,3R)-2-[(1S)-1-(3,5-bis-trifluoro-methylphenyl)ethoxy]-3-(4-fluorophenyl)morpholine
QC-634
(2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine
2s,3r------s
Aprepitant Impurity 10

Chemical & Physical Properties

[ Molecular Formula ]:
C20H18F7NO2

[ Molecular Weight ]:
437.35100

[ Exact Mass ]:
437.12300

[ PSA ]:
30.49000

[ LogP ]:
5.95690

Synthetic Route

Precursor & DownStream

Precursor

  • (2S,3R)-3-(4-fluorophenyl)-4-((R)-1-phenylethyl)morpholin-2-yl 3,5-bis(trifluoromethyl)benzoate
  • 4'-Fluoroacetophenone
  • 4-fluorophenylglyoxal hydrate

DownStream

  • Ent-Aprepitant

Related Compounds

  • (5-phenylisoxazol-3-yl)methyl 9H-xanthene-9-carboxylate
  • 5-(4-(4-Chlorobenzoyl)piperazin-1-yl)-2-(4-chlorophenyl)oxazole-4-carbonitrile
  • Carbonothioic acid, O-cyclohexyl S-2-pyridinyl ester
  • N-(4-methyl-5-(4-methylpyridin-2-yl)thiazol-2-yl)thiourea
  • 4-[(cyclopropylcarbonyl)amino]-N-(1-phenylethyl)benzamide
  • Methyl 2-amino-2-(cyclohex-2-EN-1-YL)acetate
  • 2,3,5,6-Tetrachloropentacyclo[5.4.0.0^{2,6}.0^{3,10}.0^{5,9}]undecane-4,8,11-trione
  • 2-(3-Chloropropoxy)tetrahydro-3-methyl-2H-1,3,2-oxazaphosphorine
  • 1-[(3,4-Difluorophenyl)sulfonyl]-N-[(3-fluorophenyl)(1-methyl-1H-imidazol-2-yl)methyl]-4-piperidinecarboxamide
  • 1-(4-Isopropyloxypyridin-2-yl)-propan-2-one
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