Norepinephrine hydrochloride

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Names

[ CAS No. ]:
329-56-6

[ Name ]:
Norepinephrine hydrochloride

[Synonym ]:
[2-(3,4-dihydroxyphenyl)-2-hydroxy-ethyl]ammonium chloride
(-)noradrenaline hydrochloride
L-ARTERENOL HYDROCHLORIDE
1-(3,4-dihydroxyphenyl)-2-aminoethanol hydrochloride
(-)-norepinephrine hydrochloride
(R)-(-)-noradrenaline hydrochloride
[2-(3,4-dihydroxyphenyl)-2-hydroxy-ethyl]azanium chloride
1,2-Benzenediol, 4-[(1R)-2-amino-1-hydroxyethyl]-, hydrochloride (1:1)
Levophed hydrochloride
L-NOREPINEPHRINE HYDROCHLORIDE
(R)-4-(2-Amino-1-hydroxyethyl)benzene-1,2-diol hydrochloride
4-[(1R)-2-Amino-1-hydroxyethyl]benzene-1,2-diol hydrochloride (1:1)
Aktamin hydrochloride
levophedhydrochloride
4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol hydrochloride (1:1)
(-)-ARTERENOL HYDROCHLORIDE
NOREPINEPHRINE HYDROCHLORIDE
aktaminhydrochloride
Norepinephrine (hydrochloride)

Chemical & Physical Properties

[ Density]:
1.397g/cm3

[ Boiling Point ]:
442.6ºC at 760mmHg

[ Melting Point ]:
-150ºC (dec.)

[ Molecular Formula ]:
C8H12ClNO3

[ Molecular Weight ]:
205.639

[ Flash Point ]:
221.5ºC

[ Exact Mass ]:
205.050568

[ PSA ]:
86.71000

[ LogP ]:
1.59220

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DN6475000
CHEMICAL NAME :
Benzyl alcohol, alpha-(aminomethyl)-3,4-dihydroxy-, hydrochloride, (-)-
CAS REGISTRY NUMBER :
329-56-6
LAST UPDATED :
199109
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H11-N-O3.Cl-H
MOLECULAR WEIGHT :
205.66
WISWESSER LINE NOTATION :
Z1YQR CQ DQ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
132 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
29 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraduodenal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
26 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 99,45,1950

Safety Information

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R25

[ RIDADR ]:
UN 2811 6.1/PG 3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2922509090

Synthetic Route

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds

  • DL-Norepinephrine hydrochloride
  • (±)-NOREPINEPHRINE HYDROCHLORIDE
  • 6-Fluoronorepinephrine hydrochloride
  • Norepinephrine Impurity 19 HCl
  • Norepinephrine Bitartrate
  • DL-Norepinephrine-d3 hydrochloride
  • 2-[5-(2-methoxyethyl)-1-pentyl-1H-1,2,3-triazol-4-yl]acetamide
  • 2-{1-[2-(dimethylamino)ethyl]-5-(2-methoxyethyl)-1H-1,2,3-triazol-4-yl}acetamide
  • 2-[5-(2-methoxyethyl)-1-(2-methylpropyl)-1H-1,2,3-triazol-4-yl]acetamide
  • 2-[1-(cyclopropylmethyl)-5-(2-methoxyethyl)-1H-1,2,3-triazol-4-yl]acetamide
  • 2-[1-(2-ethoxyethyl)-5-(2-methoxyethyl)-1H-1,2,3-triazol-4-yl]acetamide
  • 4-(1H-imidazol-5-yloxy)-4-methylpiperidine
  • 2-[1-(3-methoxy-2-methylpropyl)-5-(2-methoxyethyl)-1H-1,2,3-triazol-4-yl]acetamide
  • 2-[1-butyl-5-(oxan-4-yl)-1H-1,2,3-triazol-4-yl]acetamide
  • 2-[1-cyclopropyl-5-(oxan-4-yl)-1H-1,2,3-triazol-4-yl]acetamide
  • 2-[1-(2-ethoxyethyl)-5-(oxan-4-yl)-1H-1,2,3-triazol-4-yl]acetamide
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