4-Methoxybenzohydrazide

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Names

[ Name ]:
4-Methoxybenzohydrazide

[Synonym ]:
Anisic hydrazide
4-Methoxybenzoylhydrazine
4-methoxybenzoyl hydrazide
p-Anisic Hydrazide
p-Anisohydrazide
EINECS 221-952-5
MFCD00017073
4-Methoxybenzoic acid hydrazide
p-Anisoylhydrazine
Benzoic acid, 4-methoxy-, hydrazide
anisohydrazide
4-methoxyphenyl-1-carbohydrazide
p-methoxy-benzoic acid hydrazide
4-Methoxybenzohydrazide
4-Methoxybenzhydrazide
P-ANISIC ACID HYDRAZIDE
Anisoylhydrazine

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Melting Point ]:
136-140 °C(lit.)

[ Molecular Formula ]:
C₈H₁₀N₂O₂

[ Molecular Weight ]:
166.177

[ Exact Mass ]:
166.074234

[ PSA ]:
64.35000

[ LogP ]:
0.25

[ Index of Refraction ]:
1.558

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ4800000

CHEMICAL NAME :: p-Anisic acid, hydrazide

CAS REGISTRY NUMBER :: 3290-99-1

BEILSTEIN REFERENCE NO. :: 0389017

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H10-N2-O2

MOLECULAR WEIGHT :: 166.20

WISWESSER LINE NOTATION :: ZMVR DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 178 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00894 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 12 gm/kg/22W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :: 34ZRA9 "Proceedings of the Quadrennial Conference on Cancer, 3rd, 1965," Severi, L., ed., Perugia, Italy, Univ. of Perugia, 1966 Volume(issue)/page/year: -,869,1965

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
BZ4800000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Methyl anisate
p-Anisic acid
3-(4-methoxyphenyl)-4-(4-methylphenyl)-5-(phenoxymethyl)-1,2,4-triazol e
DY131
ETHYL 2-[(4-METHOXYBENZOYL)AMINO]ACETATE
Ethyl 4-methoxybenzoate
N-(cyclohexylideneamino)-4-methoxybenzamide
4-(5-METHYL-1,3,4-OXADIAZOL-2-YL)PHENOL
2-(4-methoxyphenyl)-1,3,4-oxadiazole
4-Methoxybenzamide

Articles

Metallodynamers: neutral double-dynamic metallosupramolecular polymers.

Chem. Asian J. 3(8-9) , 1324-35, (2008)

Nine neutral dynamic metallosupramolecular polymers (metallodynamers) based on acyl hydrazone derived metal coordination centers (Co(2+), Ni(2+), Zn(2+), and Cd(2+)) were generated through self-assemb...