2-Oxa-5-azabicyclo[2.2.2]octan-3-one,8,8-dimethyl-,(1R,4R)-(9CI)

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Names

[ CAS No. ]:
329041-28-3

[ Name ]:
2-Oxa-5-azabicyclo[2.2.2]octan-3-one,8,8-dimethyl-,(1R,4R)-(9CI)

[Synonym ]:
Cebranopadol

Chemical & Physical Properties

[ Molecular Formula ]:
C8H13NO2

[ Molecular Weight ]:
155.19400

[ Exact Mass ]:
155.09500

[ PSA ]:
38.33000

[ LogP ]:
0.62870

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Precursor & DownStream

Precursor

  • (1R,4R)-8,8-dimethyl-5-((R)-1-phenylethyl)-2-oxa-5-azabicyclo[2.2.2]octan-3-one
  • (2R)-3,3-dimethyl-2-(1-(R)-phenyl-ethylamino)-hex-5-enenitrile
  • (3R,6R)-6-(hydroxymethyl)-4,4-dimethyl-3-(((R)-1-phenylethyl)amino)tetrahydro-2H-pyran-2-one
  • 2,2-Dimethyl-4-pentenal

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 3-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanamido]methyl}-4-methylpentanoic acid
  • 3-{[(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]methyl}-4-methylpentanoic acid
  • 3-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pent-4-ynamido]methyl}-4-methylpentanoic acid
  • (3S)-3-({5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}formamido)butanoic acid
  • (3S)-3-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2,4-trimethylpentanamido]butanoic acid
  • (3S)-3-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4,4-trifluorobutanamido]butanoic acid
  • (3S)-3-[6-cyano-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanamido]butanoic acid
  • (3S)-3-{[1-benzyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pyrrolidin-3-yl]formamido}butanoic acid
  • (3S)-3-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)spiro[3.3]heptan-2-yl]formamido}butanoic acid
  • (3S)-3-{2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxan-4-yl]acetamido}butanoic acid