Boc-His(Trt)-OH

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Names

[ CAS No. ]:
32926-43-5

[ Name ]:
Boc-His(Trt)-OH

[Synonym ]:
BOC-L-HIS(TRT)-OH
BOC-HIS(TRT)-OH
(S)-2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanoic acid
MFCD00153307
N-(tert-Butoxycarbonyl)-1-trityl-L-histidine
His(Trt)-OH
N-T-BUTOXYCARBONYL-N-TAU-TRITYL-L-HISTIDINE
N-Boc-His(Trt)-OH
L-Histidine, N-[(1,1-dimethylethoxy)carbonyl]-1-(triphenylmethyl)-
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-1-trityl-L-histidine
Boc-His(trt)
BOC-N-IM-TRITYL-L-HISTIDINE

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
667.5±55.0 °C at 760 mmHg

[ Melting Point ]:
~130 °C (dec.)

[ Molecular Formula ]:
C30H31N3O4

[ Molecular Weight ]:
497.585

[ Flash Point ]:
357.5±31.5 °C

[ Exact Mass ]:
497.231445

[ PSA ]:
93.45000

[ LogP ]:
5.59

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.594

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
T+

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933290090

Synthetic Route

Precursor & DownStream

Precursor

  • Nα-(tert-butyloxy)carbonyl-Nim-triphenylmethyl-L-histidine methyl ester
  • Di-tert-butyl dicarbonate
  • H-His(Trt)-OH
  • Triphenylmethyl Chloride
  • 1,Nα-bis-benzyloxycarbonyl-histidine methyl ester
  • L-Histidine
  • methyl (2S)-2-amino-3-(1H-imidazol-5-yl)propanoate
  • N-Cbz-L-histidine
  • Z-His-Ome
  • Nα-benzyloxycarbonyl-Nim-triphenylmethyl-L-histidine methyl ester

DownStream

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Solid-phase synthesis of C-terminal azapeptides.

J. Pept. Sci. 21 , 387-91, (2015)

The solid-phase synthesis of azapeptides possessing a C-terminal aza-residue has been accomplished by a protocol featuring regioselective alkylation of benzhydrylidene-aza-glycinamide and illustrated ...


More Articles


Related Compounds

  • Boc-His(trt)-aib-OH
  • Boc-D-His(Trt)-OH
  • Boc-His-OH
  • Fmoc-His(Trt)-OH
  • H-His(Trt)-OH
  • TRT-HIS(TRT)-OH
  • 2-fluoro-N-(4-(p-tolyl)-1,2,5-oxadiazol-3-yl)benzamide
  • 1-[Phenyl(1H-pyrazol-1-yl)((2)H)methyl]-1H-pyrazole
  • N-[3-acetyl-10-bromo-6-(2-methylpropyl)-7-oxospiro[1,3,4-thiadiazoline-2,3'-in doline]-5-yl]acetamide
  • 3-[[6-[3,5-Bis(decyloxy)phenoxy]-1-oxohexyl][(4-carboxyphenyl)methyl]amino]benzoic acid
  • 3-(1-{[(Tert-butoxy)carbonyl]amino}-2-hydroxyethyl)benzoic acid
  • 2-Amino-3-benzoyl-7-methylindolizine-1-carbonitrile
  • ethyl (1R,9R)-6-oxo-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-diene-11-carboxylate
  • (E)-2-cyano-3-[2,5-dimethyl-1-[3-(trifluoromethyl)phenyl]pyrrol-3-yl]-N-(2,4,6-trimethylphenyl)prop-2-enamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • ethyl 2-(3-(4-chlorobenzyl)-1,7-dimethyl-2,4-dioxo-3,4-dihydro-1H-imidazo[2,1-f]purin-8(2H)-yl)acetate