TN-16

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Names

[ CAS No. ]:
33016-12-5

[ Name ]:
TN-16

[Synonym ]:
2,3`-ANHYDROTHYMIDINE-D3
3-[1-(Phenylamino)ethylidene]-5-(phenylmethyl)-2,4-pyrrolidinedione

Chemical & Physical Properties

[ Density]:
1.249g/cm3

[ Boiling Point ]:
532.7ºC at 760 mmHg

[ Melting Point ]:
182-185 °C

[ Molecular Formula ]:
C19H18N2O2

[ Molecular Weight ]:
306.35800

[ Flash Point ]:
195.5ºC

[ Exact Mass ]:
306.13700

[ PSA ]:
58.20000

[ LogP ]:
3.08450

[ Index of Refraction ]:
1.648

[ Storage condition ]:
2-8℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H317-H400

[ Precautionary Statements ]:
P273-P280

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
43-50/53

[ Safety Phrases ]:
36/37-60-61

[ RIDADR ]:
UN 3077 9 / PGIII

Articles

CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly.

J. Cell Sci. 128 , 4572-87, (2015)

Although it is generally accepted that chromatin containing the histone H3 variant CENP-A is an epigenetic mark maintaining centromere identity, the pathways leading to the formation and maintenance o...

Inhibition of microtubule assembly in vitro by TN-16, a synthetic antitumor drug.

FEBS Lett. 155(2) , 273-6, (1983)

An antitumor drug, 3-(1-anilinoethylidene)-5-benzylpyrrolidine-2,4-dione (TN-16) inhibited the assembly of porcine brain microtubules in vitro. The assembly induced by taxol was also suppressed by the...

Localization of Fas ligand in cytoplasmic granules of CD8+ cytotoxic T lymphocytes and natural killer cells: participation of Fas ligand in granule exocytosis model of cytotoxicity.

Biochem. Biophys. Res. Commun. 296(2) , 328-36, (2002)

Fas ligand (FasL) has been implicated in cytotoxic T lymphocyte (CTL)- and natural killer (NK) cell-mediated cytotoxicity. In the present study, we investigated the localization of FasL in murine CTL ...


More Articles

Related Compounds

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  • 7,16-Diphenyl-1,5,10,14-tetraazatricyclo[14.2.2.27,10]docosane
  • 10,16-dihydroxyhexadecanoic acid
  • (20β)-16-[(1R)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indol-1-yl]-17-norcorynan
  • (1R)-1-(3-Fluoro-4-methoxyphenyl)prop-2-enylamine
  • (1R)-1-(2,6-Difluorophenyl)prop-2-enylamine
  • (1R)-1-(2,5-Difluorophenyl)prop-2-enylamine
  • (1R)-1-(3,4-Difluorophenyl)prop-2-enylamine
  • (1R)-1-(3-Chloro-2-fluorophenyl)prop-2-enylamine
  • 1-[2-(3-Bromophenoxy)ethyl]-1H-pyrazole-4-carboxylic acid
  • N,1,3,4-Tetramethyl-1H-pyrazol-5-amine
  • (4-Tert-butoxyphenyl)-trimethoxy-silane
  • 1-Fluorotetracosane
  • Ethyl 2-azabicyclo[4.1.0]heptane-1-carboxylate
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