TN-16
Suppliers
Names
[ CAS No. ]:
33016-12-5
[ Name ]:
TN-16
[Synonym ]:
2,3`-ANHYDROTHYMIDINE-D3
3-[1-(Phenylamino)ethylidene]-5-(phenylmethyl)-2,4-pyrrolidinedione
Chemical & Physical Properties
[ Density]:
1.249g/cm3
[ Boiling Point ]:
532.7ºC at 760 mmHg
[ Melting Point ]:
182-185 °C
[ Molecular Formula ]:
C19H18N2O2
[ Molecular Weight ]:
306.35800
[ Flash Point ]:
195.5ºC
[ Exact Mass ]:
306.13700
[ PSA ]:
58.20000
[ LogP ]:
3.08450
[ Index of Refraction ]:
1.648
[ Storage condition ]:
2-8℃
MSDS
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H317-H400
[ Precautionary Statements ]:
P273-P280
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
43-50/53
[ Safety Phrases ]:
36/37-60-61
[ RIDADR ]:
UN 3077 9 / PGIII
Articles
J. Cell Sci. 128 , 4572-87, (2015)
Although it is generally accepted that chromatin containing the histone H3 variant CENP-A is an epigenetic mark maintaining centromere identity, the pathways leading to the formation and maintenance o...
FEBS Lett. 155(2) , 273-6, (1983)
An antitumor drug, 3-(1-anilinoethylidene)-5-benzylpyrrolidine-2,4-dione (TN-16) inhibited the assembly of porcine brain microtubules in vitro. The assembly induced by taxol was also suppressed by the...
Biochem. Biophys. Res. Commun. 296(2) , 328-36, (2002)
Fas ligand (FasL) has been implicated in cytotoxic T lymphocyte (CTL)- and natural killer (NK) cell-mediated cytotoxicity. In the present study, we investigated the localization of FasL in murine CTL ...