Z-Pro-ONp

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Names

[ CAS No. ]:
3304-59-4

[ Name ]:
Z-Pro-ONp

[Synonym ]:
Carbobenzyloxy-L-proline p-nitrophenyl ester
CARBOBENZYLOXY-L-PROLINE 4-NITROPHENYL ESTER
(S)-1-Benzyl 2-(4-nitrophenyl) pyrrolidine-1,2-dicarboxylate
N-benzyloxycarbonyl-L-proline p-nitrophenyl ester
MFCD00020828
1,2-Pyrrolidinedicarboxylic acid, 2-(4-nitrophenyl) 1-(phenylmethyl) ester, (2S)-
carbobenzyloxy-l-prolinep-nitrophenylester
Z-L-PROLINE NITROPHENYL ESTER
EINECS 221-981-3
P-NITROPHENYLCARBOBENZOXY-L-PROLINE
Z-PROLINE-ONP
N-CARBOBENZOXY-L-PROLINE-P-NITROPHENYL ESTER
N-CBZ-L-PROLINE P-NITROPHENYL ESTER
L-Proline, carbobenzyloxy-, p-nitrophenyl ester
N-carbobenzoxy-DL-proline p-nitrophenyl ester
1-Benzyl 2-(4-nitrophenyl) (2S)-pyrrolidine-1,2-dicarboxylate
benzyloxycarbonyl-L-proline p-nitrophenyl ester
1-Benzyl 2-(4-nitrophenyl) (2S)-1,2-pyrrolidinedicarboxylate
carbobenzyloxy-l-prolinp-nitrophenylester
Z-L-PROLINE 4-NITROPHENYL ESTER
Z-L-Pro-ONp

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
541.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H18N2O6

[ Molecular Weight ]:
370.356

[ Flash Point ]:
281.4±30.1 °C

[ Exact Mass ]:
370.116486

[ PSA ]:
101.66000

[ LogP ]:
2.95

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.611

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UY0750000
CHEMICAL NAME :
1,2-Pyrrolidinedicarboxylic acid, 1-benzyl p-nitrophenyl ester, L-
CAS REGISTRY NUMBER :
3304-59-4
BEILSTEIN REFERENCE NO. :
0056776
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C19-H18-N2-O6
MOLECULAR WEIGHT :
370.39
WISWESSER LINE NOTATION :
T5KTJ AVO A1R& BVOR DNW -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02163

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UY0750000

Precursor & DownStream

Precursor

  • 4-Nitrophenol
  • Z-Pro-OH
  • ethyl 2-p-nitrophenyloxycarbonyloxyimino-2-cyanoacetate
  • Benzyl chloroformate
  • Proline
  • tris(4-nitrophenyl) phosphite
  • 4-Nitrophenyl chloroformate

DownStream

  • Z-Pro-NH2
  • Cbz-pro-Leu-Ome
  • Z-Pro-Gly-NH2
  • Pro-Gly-Gly-OH
  • 1-(benzyloxycarbonyl)-L-prolyl-N5-carbamoyl-N-(4-nitrophenyl)-L-ornithinamide
  • Tuftsin acetate salt
  • Z-PRO-GLY-GLY-OH
  • LHRH (4-10) acetate salt

Related Compounds

  • Z-Pro-ONp
  • Z-Ant-Phe-Pro-ONp
  • Z-Pro-Gly-NH2
  • Z-Pro-Ala-OH
  • Z-Pro-Leu-Gly-NH2
  • Z-Pro-NH2
  • Thiourea, N-(3,5-dimethoxyphenyl)-N'-[4-(2-phenyldiazenyl)phenyl]-
  • Thiourea, N-[2-(3,4-dimethoxyphenyl)ethyl]-N'-[4-(2-phenyldiazenyl)phenyl]-
  • Benzo[b]thiophene-2-carboxylic acid, 3-chloro-6-[[[[4-(2-phenyldiazenyl)phenyl]amino]thioxomethyl]amino]-, methyl ester
  • Benzenesulfonamide, 4-[[[[4-(2-phenyldiazenyl)phenyl]amino]thioxomethyl]amino]-
  • Benzenesulfonamide, 4-[[[[4-(2-phenyldiazenyl)phenyl]amino]thioxomethyl]amino]-N-2-pyrimidinyl-
  • Thiourea, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-N'-[4-(2-phenyldiazenyl)phenyl]-
  • 3-Thiophenecarboxylic acid, 4,5-dimethyl-2-[[[[4-(2-phenyldiazenyl)phenyl]amino]thioxomethyl]amino]-, methyl ester
  • N~1~-(2-isopropylphenyl)glycinamide hydrochloride
  • N-[2-(4-ethoxyphenoxy)ethyl]-2-methylbenzamide
  • N-[2-(4-ethoxyphenoxy)ethyl]-2,3-dimethoxybenzamide
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