COLCHICINE, O(sup 1)-DEMETHYL-, ACETATE
Suppliers
Names
[ CAS No. ]:
3306-60-3
[ Name ]:
COLCHICINE, O(sup 1)-DEMETHYL-, ACETATE
[Synonym ]:
1-O-acetyl-1-O-demethyl-colchicine
1-Demethyl-1-acetylcolchicine
Chemical & Physical Properties
[ Density]:
1.29g/cm3
[ Boiling Point ]:
729.6ºC at 760 mmHg
[ Molecular Formula ]:
C23H25NO7
[ Molecular Weight ]:
427.44700
[ Flash Point ]:
395ºC
[ Exact Mass ]:
427.16300
[ PSA ]:
100.16000
[ LogP ]:
3.17920
[ Index of Refraction ]:
1.587
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GH0881000
- CHEMICAL NAME :
- Colchicine, O(sup 1)-demethyl-, acetate
- CAS REGISTRY NUMBER :
- 3306-60-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C23-H25-N-O7
- MOLECULAR WEIGHT :
- 427.49
- WISWESSER LINE NOTATION :
- L B677 MV&T&J COV1 DO1 EO1 JMV1 OO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 88 mg/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,257,1981