1-phenylpropan-2-ylurea

Names

[ CAS No. ]:
33061-37-9

[ Name ]:
1-phenylpropan-2-ylurea

[Synonym ]:
1-Benzyl-ethyl-harnstoff

Chemical & Physical Properties

[ Density]:
1.078g/cm3

[ Boiling Point ]:
306.1ºC at 760 mmHg

[ Molecular Formula ]:
C10H14N2O

[ Molecular Weight ]:
178.23100

[ Exact Mass ]:
178.11100

[ PSA ]:
56.11000

[ LogP ]:
2.19060

[ Index of Refraction ]:
1.544

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YT8379000
CHEMICAL NAME :
Urea, (alpha-methylphenethyl)-
CAS REGISTRY NUMBER :
33061-37-9
BEILSTEIN REFERENCE NO. :
2096369
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H14-N2-O
MOLECULAR WEIGHT :
178.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 6,281,1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 6,281,1971

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • trans-4-Methylaminorex
  • Phenylpropanolamine
  • Sodium cyanate
  • rac AMphetaMine Hydrochloride
  • N-Nitrocarbamide
  • Benzeneethanamine, a-methyl-
  • Urea

DownStream

Related Compounds

  • 1-phenylpropan-2-ylurea
  • 1-phenylpropan-2-yl 3-oxobutanoate
  • 1-phenylpropan-2-ylselanylbenzene
  • (1-phenylpropan-2-ylideneamino)thiourea
  • (1-phenylpropan-2-ylideneamino)urea
  • 1-phenylpropan-2-one O-naphthalen-2-ylsulfonyl oxime
  • Thalidomide-C3-PEG5-OH
  • (3-Chloro-5-fluoro-4-isopropoxyphenyl)methanol
  • 2-Amino-3-(4-cyano-3-fluorophenyl)propanoic acid;hydrochloride
  • N-({[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl}methyl)-4-(trifluoromethyl)pyrimidine-2-carboxamide
  • 4-[1-(5-Chloropyrimidin-2-yl)piperidine-3-carbonyl]morpholine
  • 1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3,3-difluoro-4-methylpiperidine-4-carboxylic acid
  • (3R)-3-Ethyl-4-(5-fluorosulfonyloxypyridine-3-carbonyl)morpholine
  • N-[(4-{4-[(1H-imidazol-2-yl)methyl]piperidine-1-carbonyl}phenyl)methyl]prop-2-enamide
  • N-[2-(1H-inden-3-yl)ethyl]prop-2-enamide
  • tert-Butyl 3-(2-amino-4-(ethoxycarbonyl)phenoxy)azetidine-1-carboxylate