3,4,5-Trichloropyridine

Names

[ Name ]:
3,4,5-Trichloropyridine

[Synonym ]:
3,4,5-Trichlor-pyridin
3,4,5-Trichloropyridine
MFCD00051685
3,4,5-trichloro-pyridine
Pyridine, 3,4,5-trichloro-

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
209.6±35.0 °C at 760 mmHg

[ Melting Point ]:
75-77°C

[ Molecular Formula ]:
C₅H₂Cl₃N

[ Molecular Weight ]:
182.43

[ Flash Point ]:
100.2±11.5 °C

[ Exact Mass ]:
180.925278

[ PSA ]:
12.89000

[ LogP ]:
2.62

[ Vapour Pressure ]:
0.3±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.573

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Pyridine
3,5-Dichloropyridin-4-ol
Chlorine
Hydrochloric acid
4-Pyridinamine,N-nitro-
3,4,5-Trichloropyridine-2-carboxylic acid
Glycerol

DownStream

1-(3,4-DIPHENYL-5-PIPERIDINO-THIEN-2-YL)-3-(2,5-DIHYDRO-3,4-DIPHENYL-5-PIPERIDIN-1-YLIDENE-ONIUM-THIEN-2-YLIDENE)-2-OXO-CYCLOBUTEN-4-OLATE
3,5-Dichloro-4-pyridinethiol
4-Amino-3,5-dichloropyridine
3,5-Dichloropyridin-4-ol
USP7/USP47 inhibitor
1-(3,5-Dichloro-4-pyridinyl)-1,4-diazepane

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

A general analytical platform and strategy in search for illegal drugs.

J. Pharm. Biomed. Anal. 100 , 215-29, (2014)

An effective screening procedure to identify and quantify active pharmaceutical substances in suspected illegal medicinal products is described. The analytical platform, consisting of accurate mass de...

Application of quantitative NMR for purity determination of standard ACE inhibitors.

J. Pharm. Biomed. Anal. 114 , 190-9, (2015)

This study investigated the accuracy of the quantitative NMR method for purity determination of ACE inhibitors reference standards and the discovery of two pairs of new diastereoisomers. Six types of ...

Use and qualification of primary and secondary standards employed in quantitative ¹H NMR spectroscopy of pharmaceuticals.

J. Pharm. Biomed. Anal. , doi:10.1016/j.jpba.2013.09.010, (2013)

Standards are required in quantitative NMR (qNMR) to obtain accurate and precise results. In this study acetanilide was established and used as a primary standard. Six other chemicals were selected as...

2-Bromo-3,4,5-trichloropyridine
2-Methyl-3,4,5-trichloropyridine
2,6-difluoro-3,4,5-trichloropyridine
3,4,5-trichloropyridine-2-carboxamide
3,4,5-trichloropyridine-2-carbonitrile
3,4,5-Trichloropyridine-2-carboxylic acid
N-[3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazol-5-yl]-5,7-dimethyl-4-oxo-4H-chromene-2-carboxamide
N-[3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazol-5-yl]-6,8-dimethyl-4-oxo-4H-chromene-2-carboxamide
N-(furan-2-ylmethyl)-N-[(5-methylfuran-2-yl)methyl]-2-[4-(1H-tetrazol-1-yl)phenoxy]acetamide
N-(4-chlorobenzyl)-4-oxo-N-(pyridin-2-yl)-4H-chromene-2-carboxamide
N-(naphthalen-1-ylmethyl)-4-oxo-N-(pyridin-2-yl)-4H-chromene-2-carboxamide
Methyl 6-acetyl-2-(2-(thiophen-2-yl)acetamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
Methyl 3-({[(1-cyanocycloheptyl)carbamoyl]methyl}amino)benzoate
N-(1-cyanocyclopentyl)-2-[(3-acetamido-2-methylphenyl)amino]acetamide
n-(3-(Benzo[d]thiazol-2-ylamino)propyl)methanesulfonamide
(4-(3-Chlorophenyl)piperazin-1-yl)(2-(phenylamino)thiazol-4-yl)methanone

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