2,2'-[4-(2-Hydroxyethylamino)-3-nitrophenylimino]diethanol
Suppliers
Names
[ CAS No. ]:
33229-34-4
[ Name ]:
2,2'-[4-(2-Hydroxyethylamino)-3-nitrophenylimino]diethanol
[Synonym ]:
2,2'-(4-(2-hydroxyethylamino)-3-nitro-phenylimino
EINECS 251-410-3
N1,N4,N4-Tris(2-hydroxyethyl)-2-nitro-1,4-phenylenediamine
HC Blue no. 2
2,2′-[4-(2-Hydroxyethylamino)-3-nitrophenylimino]diethanol
MFCD00071762
2,2'-[4-(2-HydroxyethylaMino)-3-nitrophenyliMino]diethanol
HC BLUE #2
Chemical & Physical Properties
[ Density]:
1.421 g/cm3
[ Boiling Point ]:
582.7ºC at 760 mmHg
[ Melting Point ]:
108-111 °C(lit.)
[ Molecular Formula ]:
C12H19N3O5
[ Molecular Weight ]:
285.29600
[ Exact Mass ]:
285.13200
[ PSA ]:
121.78000
[ LogP ]:
0.38620
[ Index of Refraction ]:
1.672
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KL2880000
- CHEMICAL NAME :
- Ethanol, 2,2'-((4-((2-hydroxyethyl)amino)-3-nitrophenyl)imino) di-
- CAS REGISTRY NUMBER :
- 33229-34-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 17
- MOLECULAR FORMULA :
- C12-H19-N3-O5
- MOLECULAR WEIGHT :
- 285.34
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17500 mg/kg/14D-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition Nutritional and Gross Metabolic - weight loss or decreased weight gain
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - rabbit Liver
- DOSE/DURATION :
- 50 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 241,145,1990 *** REVIEWS *** IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,143,1993 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,143,1993 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,143,1993
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
KL2880000
[ HS Code ]:
2922199090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922199090
[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Macromol. Chem. Phys. 213(2) , 234-42, (2012)
Natl. Toxicol. Program Tech. Rep. Ser. 293 , 1-192, (1985)
Toxicology and carcinogenesis studies of HC Blue No. 2 (approximately 98% pure), a semipermanent hair dye, were conducted by administering the test chemical in feed for 103 weeks to groups of 50 F344/...
IARC Monogr. Eval. Carcinog. Risks Hum. 57 , 143-51, (1993)