2-Benzoyl-1, 1-bis(2-chloroethyl)hydrazine

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Names

[ CAS No. ]:
33330-30-2

[ Name ]:
2-Benzoyl-1, 1-bis(2-chloroethyl)hydrazine

Chemical & Physical Properties

[ Density]:
1.247g/cm3

[ Molecular Formula ]:
C11H14Cl2N2O

[ Molecular Weight ]:
261.14800

[ Exact Mass ]:
260.04800

[ PSA ]:
32.34000

[ LogP ]:
2.50190

[ Index of Refraction ]:
1.555

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG4428000
CHEMICAL NAME :
Benzoic acid, 2,2-bis(2-chloroethyl)hydrazide
CAS REGISTRY NUMBER :
33330-30-2
BEILSTEIN REFERENCE NO. :
2618105
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H14-Cl2-N2-O
MOLECULAR WEIGHT :
261.17
WISWESSER LINE NOTATION :
G2N2GMVR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
175 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 8,543,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01135

Synthetic Route

Precursor & DownStream

Precursor

  • N,N-bis(2-hydroxyethyl)benzohydrazide
  • Benzohydrazide

DownStream


Related Compounds

  • N,N-bis(2-hydroxyethyl)benzohydrazide
  • 2-acridin-9-yl-1,1-bis(2-chloroethyl)hydrazine,hydrochloride
  • 1,1-bis(2-chloroethyl)hydrazine
  • bis(2-chloroethyl)-(pyridine-4-carbonylamino)azanium,chloride
  • 1,1-bis(2-chloroethyl)-3-ethyl-urea
  • 1,1-bis(2-chloroethyl)-3-heptyl-thiourea
  • 3-formyl-5H,6H,7H-pyrrolo[1,2-a]imidazole-2-carboxylic acid
  • rac-(1R,2R)-1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-fluoro-2,3-dihydro-1H-indene-2-carboxylic acid
  • rac-tert-butyl (1R,2S)-2-amino-7-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylate
  • 7-Oxa-9-azaspiro[4.5]decane-8-carboxylic acid
  • {1,4-Dioxaspiro[5.6]dodecan-2-yl}methanol
  • 2-(1-Aminoethyl)-4-tert-butyl-6-methylphenol
  • 4-[Amino(cyclopropyl)methyl]-2-bromo-5-fluorophenol
  • 1-[5-(1,3-Dioxolan-2-yl)-1,3-thiazol-2-yl]pentan-1-one
  • 1-[2-(2-Fluoro-1-hydroxy-2-methylpropyl)-1,3-thiazol-4-yl]ethan-1-one
  • 1-[5-(2-Aminoethyl)-4-methyl-1,3-thiazol-2-yl]butan-1-ol
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