Erythromycin A Enol Ether

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Names

[ CAS No. ]:
33396-29-1

[ Name ]:
Erythromycin A Enol Ether

[Synonym ]:
9-Deoxo-6-deoxy-6,9-epoxy-8,9-didehydroerythromycin
8,9-anhydroerythromycin A 6,9-hemiacetal
6,9-Epoxy-8,9-didehydro-9-deoxo-6-deoxyerythromycin
8,9-anhydroerythromycin A 6,9-hemiketal
erythromycin hemiketal
8,9-anhydroerythromycin 6,9-hemiketal
6-Deoxy-9-deoxo-8,9-didehydro-6,9-epoxyerythromycin
8,9-anhydroerythromycin A
EM 523
Erythromycin Impurity 5

Chemical & Physical Properties

[ Density]:
1.2g/cm3

[ Boiling Point ]:
791.6ºC at 760mmHg

[ Melting Point ]:
133-135ºC

[ Molecular Formula ]:
C37H65NO12

[ Molecular Weight ]:
715.91100

[ Flash Point ]:
432.6ºC

[ Exact Mass ]:
715.45100

[ PSA ]:
165.84000

[ LogP ]:
2.89230

[ Index of Refraction ]:
1.542

[ Storage condition ]:
-20°C Freezer

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Erythromycin
  • Pseudoerythromycin A enol ether

DownStream

  • Anhydroerythromycin A

Articles

Sensitive high-performance liquid chromatographic determination of EM523, a new erythromycin derivative, in human plasma and urine with ultraviolet detection using column switching.

J. Chromatogr. A. 616(1) , 144-50, (1993)

A sensitive high-performance liquid chromatographic (HPLC) method using column switching is described for the determination of EM523 (I), a new erythromycin derivative, in human plasma and urine. The ...

Comparison of the motor-stimulating action of EM523, an erythromycin derivative, and prostaglandin F2 alpha in conscious dogs.

Jpn. J. Pharmacol. 63(2) , 209-17, (1993)

The effect of EM523 [de(N-methyl)-N-ethyl-8,9-anhydroerythromycin A 6,9-hemiacetal], an erythromycin derivative, on gastrointestinal motility was investigated using conscious dogs in the fasting state...

EM523L, a nonpeptide motilin agonist, stimulates gastric emptying and pancreatic polypeptide secretion.

Peptides 17(6) , 895-900, (1996)

We investigated the efficacy and the mechanism of action of EM523L, a nonpeptide motilin agonist (motilide), on the stimulation of gastric emptying and on the release of gut peptides after ingestion o...


More Articles

Related Compounds

  • Pseudoerythromycin A enol ether
  • Erythromycin A 6,9-Imino Ether
  • Erythromycin A 9,11-Imino Ether
  • Erythromycin 2'-Propionate
  • erythromycin-A, hydrochloride
  • erythromycin A oxime 11,12-carbonate
  • 2-Cyclopentene-1-acetamide, N-(2-hydroxy-3-methoxypropyl)-
  • N-[(Pyrrolidin-3-yl)methyl]methanesulfonamide
  • 1-(1-methyl-1H-pyrazol-4-yl)cyclopentan-1-amine
  • 4-(Ethyl-3-methylanilino)butyric acid ethyl ester
  • 1-(3-Methyl-1,2-oxazol-5-yl)propan-1-one
  • Acetamide, 2-[(2,4-dimethylcyclohexyl)amino]-N-methyl-
  • 2-[3-(Trifluoromethyl)piperidin-1-yl]aniline
  • 6-[4-(Trifluoromethyl)piperidin-1-yl]pyridin-3-amine
  • 5-(4-(Trifluoromethyl)piperidin-1-yl)pentan-1-amine
  • 1-(1-ethyl-1H-pyrazol-4-yl)cyclopentan-1-amine
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