Mdivi-1

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Names

[ CAS No. ]:
338967-87-6

[ Name ]:
Mdivi-1

[Synonym ]:
4(1H)-Quinazolinone, 3-(2,4-dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-
HMS575G09
3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone
Mdivi-1
3-(2,4-Dichloro-5-methoxyphenyl)-2-sulfanylquinazolin-4(3H)-one
3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone
Mitochondrial division inhibitor 1

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
522.5±60.0 °C at 760 mmHg

[ Melting Point ]:
289 °C

[ Molecular Formula ]:
C15H10Cl2N2O2S

[ Molecular Weight ]:
353.223

[ Flash Point ]:
269.8±32.9 °C

[ Exact Mass ]:
351.984009

[ PSA ]:
82.92000

[ LogP ]:
3.85

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.729

[ Storage condition ]:
Store at -20°C

[ Water Solubility ]:
DMSO: >20mg/mL

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Nitrobenzoyl chloride
  • 5-Amino-2,4-dichloroanisole
  • N-(2,4-dichloro-5-methoxyphenyl)-2-nitrobenzamide

DownStream

Articles

Dynamin-related protein Drp1 and mitochondria are important for Shigella flexneri infection.

Int. J. Med. Microbiol. 304(5-6) , 530-41, (2014)

Shigella infection in epithelial cells induces cell death which is accompanied by mitochondrial dysfunction. In this study the role of the mitochondrial fission protein, Drp1 during Shigella infection...


More Articles

Related Compounds

  • Propane,1,1-bis(ethylsulfonyl)-2-methyl-
  • Pyridinium, 1- (2-hydroxy[1,1:3,1-terphenyl]-5-yl)-2,4, 6-triphenyl-, perchlorate (salt)
  • Cyclohexanecarboxylicacid, 1-methyl-3-oxo-, ethyl ester
  • 2-[1-(2-hydroxy-3,5-dimethylphenyl)cyclohexyl]-4,6-dimethylphenol
  • 3-[1-(2,5-dimethylthiophen-3-yl)octadecyl]-4-propan-2-ylideneoxolane-2,5-dione
  • trans-1,2-Dimethylcyclohexane
  • 3-(3-Iodophenoxy)propanal
  • (5-Methylpyrazin-2-yl)methanamine hydrochloride
  • Ethyl 1-oxa-5-thiaspiro[2.4]heptane-2-carboxylate 5,5-dioxide
  • 3',4'-Dihydrospiro[piperidine-4,2'-pyrano[3,2-b]pyridine]-4'-one dihydrochloride
  • 5-(3-Aminobutyl)-2-methoxyphenol
  • 5-Chloropicolinamide hydrochloride
  • 4-(Pyrimidin-4-yl)butan-2-amine
  • 3-(Methylsulfanyl)azetidine hydroiodide
  • 2-Ethoxy-3-ethylpentan-1-amine
  • 4-[(4-Bromophenyl)methoxy]-2,6-dimethylaniline
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