N-DeMethyl Vandetanib

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Names

[ CAS No. ]:
338992-12-4

[ Name ]:
N-DeMethyl Vandetanib

[Synonym ]:
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazolin-4-amine

Chemical & Physical Properties

[ Molecular Formula ]:
C21H22BrFN4O2

[ Molecular Weight ]:
461.32700

[ Exact Mass ]:
460.09100

[ PSA ]:
68.30000

[ LogP ]:
5.06380

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • TERT-BUTYL 4-(((4-((4-BROMO-2-FLUOROPHENYL)AMINO)-6-METHOXYQUINAZOLIN-7-YL)OXY)METHYL)PIPERIDINE-1-CARBOXYLATE
  • 4-Bromo-2-fluoroaniline
  • 4-(4-bromo-2-fluorophenylamino)-6-methoxyquinazolin-7-ol
  • tert-Butyl 4-((tosyloxy)methyl)piperidine-1-carboxylate
  • 7-(Benzyloxy)-4-chloro-6-methoxyquinazoline
  • 7-(benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine

DownStream

  • Vandetanib(ZD6474)

Related Compounds

  • N-Demethyl Mifepristone
  • N-Demethyl Erythromycin A
  • N-Demethyl Promethazine-d3 hydrochloride
  • N-Demethyl-Benzydamine
  • N-DeMethyl Mecamylamine
  • N-Demethyl-N-formyl Clarithromycin