TERT-BUTYL 4-(((4-((4-BROMO-2-FLUOROPHENYL)AMINO)-6-METHOXYQUINAZOLIN-7-YL)OXY)METHYL)PIPERIDINE-1-CARBOXYLATE

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Names

[ CAS No. ]:
338992-20-4

[ Name ]:
TERT-BUTYL 4-(((4-((4-BROMO-2-FLUOROPHENYL)AMINO)-6-METHOXYQUINAZOLIN-7-YL)OXY)METHYL)PIPERIDINE-1-CARBOXYLATE

[Synonym ]:
qc-1063

Chemical & Physical Properties

[ Molecular Formula ]:
C26H30BrFN4O4

[ Molecular Weight ]:
561.44300

[ Exact Mass ]:
560.14300

[ PSA ]:
85.81000

[ LogP ]:
6.32040

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • tert-Butyl 4-((tosyloxy)methyl)piperidine-1-carboxylate
  • 4-(4-bromo-2-fluorophenylamino)-6-methoxyquinazolin-7-ol
  • 1-Boc-4-piperidinemethanol
  • 4-(Benzyloxy)-5-methoxy-2-nitrobenzoic acid
  • 4-(BENZYLOXY)-5-METHOXY-2-NITROBENZALDEHYDE
  • 5-methoxy-2-nitro-4-phenylmethoxybenzamide
  • 2-amino-5-methoxy-4-phenylmethoxybenzamide
  • 7-(benzyloxy)-6-methoxyquinazolin-4-ol
  • 4-(Benzyloxy)-3-methoxybenzaldehyde
  • 7-(benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine

DownStream

  • Vandetanib(ZD6474)
  • N-DeMethyl Vandetanib

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • (3S)-3-{[(benzyloxy)carbonyl]amino}-3-(4-ethylphenyl)propanoic acid
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • N-[1-(5-cyclopropyl-1H-pyrazol-3-yl)piperidin-4-yl]-2,5-dimethylfuran-3-carboxamide
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(5-butyl-1,3,4-thiadiazol-2-yl)-3-(7-methoxy-1H-indol-1-yl)propanamide
  • N-(4-fluorobenzyl)-3-(pyrazin-2-yloxy)piperidine-1-carboxamide
  • 3-(2-methoxybenzyl)-2-(((3-(p-tolyl)-1,2,4-oxadiazol-5-yl)methyl)thio)quinazolin-4(3H)-one