3,6-Dichlorosalicylic acid
Suppliers
Names
[ CAS No. ]:
3401-80-7
[ Name ]:
3,6-Dichlorosalicylic acid
[Synonym ]:
3,6-DICHLOROSALICYLIC ACID
2-Hydroxy-3,6-dichlorobenzoic acid
3,6-Dichlor-2-hydroxy-benzoesaeure
2-hydroxy-3,5-dichlorobenzoic acid
Benzoic acid,3,6-dichloro-2-hydroxy
EINECS 222-275-8
MFCD00155381
3,6-Dichloro-2-hydroxy-benzoic acid
Salicylic acid,3,6-dichloro
2-Oxy-3,6-dichlorobenzoic acid
Chemical & Physical Properties
[ Density]:
1.665 g/cm3
[ Boiling Point ]:
306.7ºC at 760 mmHg
[ Molecular Formula ]:
C7H4Cl2O3
[ Molecular Weight ]:
207.01100
[ Flash Point ]:
139.3ºC
[ Exact Mass ]:
205.95400
[ PSA ]:
57.53000
[ LogP ]:
2.39720
[ Index of Refraction ]:
1.641
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VO2500000
- CHEMICAL NAME :
- Salicylic acid, 3,6-dichloro-
- CAS REGISTRY NUMBER :
- 3401-80-7
- BEILSTEIN REFERENCE NO. :
- 2938787
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C7-H4-Cl2-O3
- MOLECULAR WEIGHT :
- 207.01
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1560 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 43(10),95,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 660 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 43(10),95,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB85-143766
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(9),55,1981 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 546 mg/kg/26W-I
- TOXIC EFFECTS :
- Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - catalases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 43(10),95,1978
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5230 ug/m3/26W-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - emphysema
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(9),55,1981
Safety Information
[ HS Code ]:
2918290000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2918290000
[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%