METHOXYPROMAZINE MALEATE

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Names

[ CAS No. ]:
3403-42-7

[ Name ]:
METHOXYPROMAZINE MALEATE

[Synonym ]:
Methopromazinhydrogenmaleat
2-Methoxypromazine maleate
Mopazine maleate
Methopromazine maleate
2-Methoxypromazin-maleat
Mopazine
EINECS 222-277-9
Methoxypromazine maleate
Tentone maleate
Metopromazine maleate

Chemical & Physical Properties

[ Boiling Point ]:
461.8ºC at 760mmHg

[ Molecular Formula ]:
C22H26N2O5S

[ Molecular Weight ]:
430.51700

[ Flash Point ]:
233.1ºC

[ Exact Mass ]:
430.15600

[ PSA ]:
115.61000

[ LogP ]:
4.02640

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SO7700000
CAS REGISTRY NUMBER :
3403-42-7
LAST UPDATED :
199712
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C18-H22-N2-O-S.C4-H4-O4
MOLECULAR WEIGHT :
430.56
WISWESSER LINE NOTATION :
T C666 BN ISJ B3N1&1 EO1 &OV1U1VO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
730 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,32,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
130 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 125,101,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
420 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,32,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
120 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,32,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,32,1972

Safety Information

[ HS Code ]:
2934300000

Customs

[ HS Code ]: 2934300000

[ Summary ]:
2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • TPN729 maleate
  • lead maleate
  • Dioctyl maleate
  • Dibutyltin Maleate Polymer n=2-3
  • (Z)-but-2-enedioic acid,(1S,5R)-3-(6,11-dihydro-5H-dibenzo[1,2-a:1',2'-e][7]annulen-11-yloxy)-8-methyl-8-azabicyclo[3.2.1]octane
  • Compazine maleate
  • 3-Benzyl-7,7-difluoro-3-azabicyclo[3.3.1]nonan-9-one
  • 5-[2-(aminomethyl)-3,3-dimethylpiperidin-1-yl]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
  • 5-[({6-azabicyclo[3.2.1]octan-3-yl}methyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
  • 5-[(3S,5S)-3-amino-5-methylpiperidin-1-yl]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
  • rac-5-[(4aR,8aS)-octahydro-2H-pyrido[4,3-b][1,4]oxazin-6-yl]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
  • rac-5-[(4aR,8aS)-octahydro-2H-pyrido[4,3-b][1,4]oxazin-4-yl]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
  • 5-{3,6-diazabicyclo[3.2.1]octan-6-yl}-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
  • 5-{4-[(1S)-1-aminoethyl]piperidin-1-yl}-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
  • 5-[({1,1-difluoro-5-azaspiro[2.4]heptan-6-yl}methyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
  • 5-({5-azaspiro[3.4]octan-7-yl}amino)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione