3,4-Difluorobenzaldehyde

Names

[ Name ]:
3,4-Difluorobenzaldehyde

[Synonym ]:
4,5-difluorobenzaldehyde
VHR CF DF
MFCD00010328
EINECS 422-180-3
3,4-Difluorobenzaldehyde
3,4-diflourobenzaldehyde
Benzaldehyde, 3,4-difluoro-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
185.1±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C₇H₄F₂O

[ Molecular Weight ]:
142.103

[ Flash Point ]:
65.6±0.0 °C

[ Exact Mass ]:
142.023026

[ PSA ]:
17.07000

[ LogP ]:
1.67

[ Vapour Pressure ]:
0.7±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.514

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ HS Code ]:
2913000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

3,4-Difluorobenzoic acid
4-(4-BOC-PIPERAZINO-1-YL)-3-FLUOROBENZALDEHYDE
(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid
4-(3,4-DIFLUOROPHENYL)-1,4,5,6-TETRAHYDRO-2-METHYL-6-OXO-3-PYRIDINECARBOXYLIC ACID
2-Fluoro-4-formyl-1-(methylsulphonyl)benzene
Benzaldehyde, 3,4-difluoro-, oxime (9CI)
(1R,2R)-Ethyl 2-(3,4-difluorophenyl)cyclopropanecarboxylate
1-(3-fluoro-4-methylsulfanyl-phenyl)propan-2-one
trans-3,4-Difluorocinnamic acid
1-(3,4-DIFLUOROPHENYL)-2-AMINOPROPANE

Customs

[ HS Code ]: 2913000090

[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

Articles

Synthesis of 3-O-acyl/3-benzylidene/3-hydrazone/3-hydrazine/17-carboxyacryloyl ester derivatives of betulinic acid as anti-angiogenic agents.

Bioorg. Med. Chem. Lett. 14(12) , 3169-72, (2004)

New 3-O-acyl, 3-benzylidene, 3-hydrazone, 3-hydrazine, 17-carboxyacryloyl ester derivatives of betulinic acid (2-6, 8-11, 13, 17, 18, 21, and 22) were synthesized and evaluated in vitro for anti-angio...