Sudoxicam

Suppliers

Names

[ CAS No. ]:
34042-85-8

[ Name ]:
Sudoxicam

[Synonym ]:
Sudoxicamum
4-hydroxy-2-methyl-N-(2-thiazole)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
N-(2-thiazolyl)-4-hydroxy-2-methyl-2H,1,2-benzothiazine-3-carboxamide 1,1-dioxide
Sudoxicamum [INN-Latin]
2H-1,2-Benzothiazine-3-carboxamide,4-hydroxy-2-methyl-N-2-thiazolyl-,1,1-dioxide
4-hydroxy-2-methyl-N-(2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
EINECS 251-808-7
SUDOXICAM

Chemical & Physical Properties

[ Density]:
1.675g/cm3

[ Melting Point ]:
240-243 °C (dec.)

[ Molecular Formula ]:
C13H11N3O4S2

[ Molecular Weight ]:
337.37400

[ Exact Mass ]:
337.01900

[ PSA ]:
136.22000

[ LogP ]:
2.73420

[ Index of Refraction ]:
1.741

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DL0710500
CHEMICAL NAME :
2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-thiazolyl-, 1,1-dioxide
CAS REGISTRY NUMBER :
34042-85-8
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C13-H11-N3-O4-S2
MOLECULAR WEIGHT :
337.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
136 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,1714,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
260 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 15,848,1972

Precursor & DownStream

Precursor

  • methyl 2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetate
  • Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide
  • Saccharin
  • 2-Aminothiazole
  • Methyl 4-hydroxy-2-methyl-(2H)-1,2-benzothiazine-3-carboxylate-1,1-dioxide

DownStream

Related Compounds

  • sudoxicam
  • 9-chloro-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
  • 3-[4-(Pentafluoroethyl)phenyl]propanenitrile
  • 1-(6-chloro-1-methyl-1H-indol-3-yl)cyclobutane-1-carbonitrile
  • 5-(2-Isocyanatoethyl)-1-benzofuran
  • 3-(difluoromethyl)-4-isocyanato-1-methyl-1H-pyrazole
  • O-[2-(3-chloro-2,6-difluorophenyl)-2-methylpropyl]hydroxylamine
  • O-[2-(2-chloro-4-methylphenyl)-2-methylpropyl]hydroxylamine
  • (1-ethyl-1H-imidazol-5-yl)methyl sulfamate
  • O-{2-[5-(trifluoromethyl)furan-2-yl]ethyl}hydroxylamine
  • 2-(4-Chloro-3-methoxyphenyl)-2-methyloxirane
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