Haloperidol Metabolite II

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Names

[ CAS No. ]:
34104-67-1

[ Name ]:
Haloperidol Metabolite II

[Synonym ]:
Haloperidol metabolite II

Chemical & Physical Properties

[ Density]:
1.247g/cm3

[ Boiling Point ]:
531.2ºC at 760 mmHg

[ Melting Point ]:
125-127°C

[ Molecular Formula ]:
C₂₁H₂₅ClFNO₂

[ Molecular Weight ]:
377.88000

[ Flash Point ]:
275.1ºC

[ Exact Mass ]:
377.15600

[ PSA ]:
43.70000

[ LogP ]:
4.21420

[ Appearance of Characters ]:
white

[ Index of Refraction ]:
1.589

[ Storage condition ]:
Refrigerator

[ Water Solubility ]:
DMSO: soluble10mg/mL

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors.

Psychopharmacology 205 , 21-33, (2009)

We evaluated the effects of haloperidol and its metabolites on capsaicin-induced mechanical hypersensitivity (allodynia) and on nociceptive pain induced by punctate mechanical stimuli in mice.Subcutan...

Determination of haloperidol and reduced haloperidol in human serum by liquid chromatography after fluorescence labeling based on the Suzuki coupling reaction.

Anal. Bioanal. Chem 386(3) , 719-24, (2006)

A simultaneous method for the determination of haloperidol (HP) and its metabolite, reduced haloperidol (RHP), in human serum was developed by means of high-performance liquid chromatography (HPLC) wi...

Plasma reduced haloperidol/haloperidol ratios in schizophrenic patients treated with high dosages of haloperidol.

Eur. Neuropsychopharmacol. 4(2) , 119-26, (1994)

Plasma haloperidol (HL) and reduced haloperidol (RH) levels were measured in 60 schizophrenic patients treated with high to very high HL doses of 40-200 mg/day. Plasma samples were obtained at steady-...