N-AcetylprocainaMide hydrochloride

Names

[ Name ]:
N-AcetylprocainaMide hydrochloride

[Synonym ]:
NAPA
Acecainide hydrochloride
EINECS 251-831-2
MFCD00012501
Acecainide HCl
N-ACETYLPROCAINAMIDE HYDROCHLORIDE
ASL-601

Chemical & Physical Properties

[ Boiling Point ]:
500ºC at 760mmHg

[ Melting Point ]:
184-186ºC(lit.)

[ Molecular Formula ]:
C₁₅H₂₄ClN₃O₂

[ Molecular Weight ]:
313.82

[ Flash Point ]:
256.2ºC

[ Exact Mass ]:
313.15600

[ PSA ]:
61.44000

[ LogP ]:
2.98250

[ Appearance of Characters ]:
powder

[ Storage condition ]:
−20°C

[ Water Solubility ]:
H2O: 50 mg/mL

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
UN 3249

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2924299090

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Phase II metabolism in human skin: skin explants show full coverage for glucuronidation, sulfation, N-acetylation, catechol methylation, and glutathione conjugation.

Drug Metab. Dispos. 43(1) , 126-39, (2014)

Although skin is the largest organ of the human body, cutaneous drug metabolism is often overlooked, and existing experimental models are insufficiently validated. This proof-of-concept study investig...

Drug-herb interaction: effect of St John's wort on bioavailability and metabolism of procainamide in mice.

Arch. Pathol. Lab. Med. 131(7) , 1094-8, (2007)

St John's wort induces the activity of the cytochrome P450 enzyme system causing treatment failure because of increased metabolism of many drugs. Procainamide is metabolized by a different pathway to ...