MTIC
Suppliers
Names
[ CAS No. ]:
3413-72-7
[ Name ]:
MTIC
[Synonym ]:
5-Monomethyltriazenoimidazole-4-carboxamide
5-(3-Monomethyl-1-triazeno)imidazole-4-carboxamide
(5E)-5-(methylaminohydrazinylidene)imidazole-4-carboxamide
5-(3-Methyl-1-triazeno)imidazole-4-carboxamide
1H-Imidazole-4-carboxamide,5-(3-methyl-1-triazenyl)
5-(3-methyltriazen-1-yl)imidazole-4-carboxamide
Imidazole-4-carboxamide,5-(3-methyl-1-triazeno)
Chemical & Physical Properties
[ Density]:
1.66g/cm3
[ Boiling Point ]:
306.7ºC at 760mmHg
[ Molecular Formula ]:
C5H8N6O
[ Molecular Weight ]:
168.15700
[ Flash Point ]:
139.3ºC
[ Exact Mass ]:
168.07600
[ PSA ]:
108.52000
[ LogP ]:
0.81790
[ Index of Refraction ]:
1.741
[ Storage condition ]:
-20°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NI4000000
- CHEMICAL NAME :
- Imidazole-4-carboxamide, 5-(3-methyl-1-triazeno)-
- CAS REGISTRY NUMBER :
- 3413-72-7
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C5-H8-N6-O
- MOLECULAR WEIGHT :
- 168.19
- WISWESSER LINE NOTATION :
- T5M CNJ DVZ ENUNM1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 775 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4450 mg/kg/14W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Reproductive - Tumorigenic effects - uterine tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Reproductive - Tumorigenic effects - uterine tumors
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - rat Cells - not otherwise specified
- DOSE/DURATION :
- 1 mmol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 36,2827,1976
Safety Information
[ HS Code ]:
2934999090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%