Celastrol

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Names

[ CAS No. ]:
34157-83-0

[ Name ]:
Celastrol

[Synonym ]:
Celasterol
(2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-2-picenecarboxylic acid
Celastrol
2-Picenecarboxylic acid, 1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-, (2R,4aS,6aS,12bR,14aS,14bR)-
Tripterine
(2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid
MFCD03424073
TRIPTERIN

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
645.7±55.0 °C at 760 mmHg

[ Melting Point ]:
185-200ºC

[ Molecular Formula ]:
C29H38O4

[ Molecular Weight ]:
450.610

[ Flash Point ]:
358.3±28.0 °C

[ Exact Mass ]:
450.277008

[ PSA ]:
74.60000

[ LogP ]:
7.08

[ Vapour Pressure ]:
0.0±4.4 mmHg at 25°C

[ Index of Refraction ]:
1.602

[ Storage condition ]:
Store at -20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T

[ Risk Phrases ]:
25

[ Safety Phrases ]:
45

[ RIDADR ]:
UN 2811 6.1 / PGIII

[ HS Code ]:
2942000000

Precursor & DownStream

Precursor

DownStream

  • Pristimerin

Customs

[ HS Code ]: 2942000000

Articles

Biological activity and safety of Tripterygium extract prepared by sodium carbonate extraction.

Molecules 17(9) , 11113-23, (2012)

The commercial preparation named “Tripterygium glycosides” prepared by column chromatography has been used for the treatment of inflammatory and autoimmune diseases with significant efficacy but concu...

Inhibitory mechanisms of celastrol on human liver cytochrome P450 1A2, 2C19, 2D6, 2E1 and 3A4.

Xenobiotica 45 , 571-7, (2015)

1. The present study was conducted to examine the possibility of herb-drug interaction by celastrol, which is a main compound isolated from Tripterygium wilfordii Hook F. using human liver microsomes ...

[Studies on sustained release solid dispersion of tripterine carried by HPMC-stearic acid].

Zhongguo Zhong Yao Za Zhi 37(20) , 3052-5, (2012)

To prepare the sustained release solid dispersion of tripterine, using HPMC-stearic acid with the intention of improving drug dissolution and controlling drug releases moderate, so that the drug perfo...


More Articles

Related Compounds

  • Celastrol
  • Celastrol-methylether
  • 5-bromo-N-(thiophen-2-yl(thiophen-3-yl)methyl)nicotinamide
  • 3-(phenylsulfonyl)-N-(thiophen-2-yl(thiophen-3-yl)methyl)propanamide
  • 8-methoxy-2-oxo-N-(thiophen-2-yl(thiophen-3-yl)methyl)-2H-chromene-3-carboxamide
  • 2-bromo-5-methoxy-N-(thiophen-2-yl(thiophen-3-yl)methyl)benzamide
  • 5-cyclopropyl-N-(thiophen-2-yl(thiophen-3-yl)methyl)isoxazole-3-carboxamide
  • N-(thiophen-2-yl(thiophen-3-yl)methyl)furan-3-carboxamide
  • 5-methyl-N-(thiophen-2-yl(thiophen-3-yl)methyl)isoxazole-4-carboxamide
  • 2-(3,5-dimethylisoxazol-4-yl)-N-(thiophen-2-yl(thiophen-3-yl)methyl)acetamide
  • 2-(2-chloro-6-fluorophenyl)-N-(thiophen-2-yl(thiophen-3-yl)methyl)acetamide
  • 1-methyl-N-(thiophen-2-yl(thiophen-3-yl)methyl)-1H-1,2,3-triazole-4-carboxamide
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