Attentil

Suppliers

Names

[ CAS No. ]:
34161-23-4

[ Name ]:
Attentil

[Synonym ]:
1-[2-(4-CHLOROPHENOXY)ACETYL]-4-[3,4-METHYLENEDIOXYBENZYL]PIPERAZINE HYDROCHLORIDE
1-(3',4'-methylenedioxybenzyl)-4-(4-chlorophenoxyacetyl)-piperazine hydrochloride
1-(1,3-benzodioxol-5-ylmethyl)-4-[(4-chlorophenoxy)acetyl]piperazinium chloride
Vigilor
1-(1,3-Benzodioxol-5-yl-methyl)-4-[(4-chlorophenoxy)acetyl]piperazine hydrochloride
Attentil
1-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-chlorophenoxy)ethanone hydrochloride
BP-662

Chemical & Physical Properties

[ Density]:
1.342g/cm3

[ Boiling Point ]:
559.3ºC at 760 mmHg

[ Molecular Formula ]:
C20H22Cl2N2O4

[ Molecular Weight ]:
425.30600

[ Flash Point ]:
292.1ºC

[ Exact Mass ]:
424.09600

[ PSA ]:
51.24000

[ LogP ]:
3.46970

[ Storage condition ]:
-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TK8220100
CHEMICAL NAME :
Piperazine, 1-(1,3-benzodioxol-5-ylmethyl)-4-((4-chlorophenoxy)ac etyl)-, monohydrochloride
CAS REGISTRY NUMBER :
34161-23-4
LAST UPDATED :
199009
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C20-H21-Cl-N2-O4.Cl-H
MOLECULAR WEIGHT :
425.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4482 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia
REFERENCE :
ACTTDZ Acta Therapeutica. (Pl. de Bastogne 8, B13, 1080 Brussels, Belgium) V.1- 1975- Volume(issue)/page/year: 11,387,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia
REFERENCE :
ACTTDZ Acta Therapeutica. (Pl. de Bastogne 8, B13, 1080 Brussels, Belgium) V.1- 1975- Volume(issue)/page/year: 11,387,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4150 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia
REFERENCE :
ACTTDZ Acta Therapeutica. (Pl. de Bastogne 8, B13, 1080 Brussels, Belgium) V.1- 1975- Volume(issue)/page/year: 11,387,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
499 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia
REFERENCE :
ACTTDZ Acta Therapeutica. (Pl. de Bastogne 8, B13, 1080 Brussels, Belgium) V.1- 1975- Volume(issue)/page/year: 11,387,1985

Safety Information

[ Hazard Codes ]:
Xn

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Acetyl chloride,2-(4-chlorophenoxy)
  • Piperazine,1,4-bis(1,3-benzodioxol-5-ylmethyl)
  • 5-(Chloromethyl)-1,3-benzodioxole

DownStream

Related Compounds

  • tert-butyl N-[5-(2-aminopropanoyl)-4-methyl-1,3-thiazol-2-yl]carbamate
  • tert-butyl N-[5-(1-amino-3-hydroxypropyl)-4-methyl-1,3-thiazol-2-yl]carbamate
  • tert-butyl N-[5-(4-aminobutan-2-yl)-4-methyl-1,3-thiazol-2-yl]carbamate
  • 4-Amino-4-(2-{[(tert-butoxy)carbonyl]amino}-4-methyl-1,3-thiazol-5-yl)butanoic acid
  • tert-butyl N-(5-{[hydroxy(methyl)amino]methyl}-4-methyl-1,3-thiazol-2-yl)carbamate
  • tert-butyl (1S,4R)-5-(2-amino-1,3-oxazol-5-yl)-2-azabicyclo[2.1.1]hexane-2-carboxylate
  • tert-butyl (1S,4R)-5-[1-(aminomethyl)-4-hydroxycyclohexyl]-2-azabicyclo[2.1.1]hexane-2-carboxylate
  • 2-(2-{[(Tert-butoxy)carbonyl]amino}-4-methyl-1,3-thiazol-5-yl)-3-methylbutanoic acid
  • 3-(2-{[(Tert-butoxy)carbonyl]amino}-4-methyl-1,3-thiazol-5-yl)butanoic acid
  • tert-butyl N-{5-[(1R)-1-hydroxyethyl]-4-methyl-1,3-thiazol-2-yl}carbamate
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.