[2-(aziridin-1-yl)piperidin-1-yl]-[4-[[4-(aziridin-1-yl)piperidin-1-yl]-oxophosphaniumyl]oxyphenoxy]-oxophosphanium
Names
[ CAS No. ]:
34180-21-7
[ Name ]:
[2-(aziridin-1-yl)piperidin-1-yl]-[4-[[4-(aziridin-1-yl)piperidin-1-yl]-oxophosphaniumyl]oxyphenoxy]-oxophosphanium
[Synonym ]:
a-205
Chemical & Physical Properties
[ Molecular Formula ]:
C20H30N4O4P2++
[ Molecular Weight ]:
452.42400
[ Exact Mass ]:
452.17400
[ PSA ]:
133.38000
[ LogP ]:
3.41820
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SZ4170000
- CHEMICAL NAME :
- Phosphinic acid, (1-aziridinyl)piperidino-, p-phenylene ester
- CAS REGISTRY NUMBER :
- 34180-21-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C20-H32-N4-O4-P2
- MOLECULAR WEIGHT :
- 454.50
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 260 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 6,145,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 418 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 6,145,1971
Safety Information
[ HS Code ]:
2933990090
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%