hydrocodone bitartrate
Names
[ CAS No. ]:
34195-34-1
[ Name ]:
hydrocodone bitartrate
[Synonym ]:
4,5-Epoxy-3-methoxy-17-methyl-morphinan-6-on,Hydrogentartrat
CODEINE IMP E
Codeine,10-hydroxy
4,5-Epoxy-3-methoxy-17-methyl-morphin-7-en-6,10-diol
Hydrocodone bitartrate salt hemi(pentahydrate)
4,5-epoxy-3-methoxy-17-methyl-morphinan-6-one,hydrogentartrate
HYDROCODONE BITARTRATE
7,8-DIDEHYDRO-4,5A-EPOXY-3-METHOXY-17-METHYLMORPHINAN-6A,10-DIOL
Chemical & Physical Properties
[ Boiling Point ]:
461.4ºC at 760mmHg
[ Melting Point ]:
198ºC
[ Molecular Formula ]:
C22H29NO10
[ Molecular Weight ]:
467.46600
[ Flash Point ]:
232.9ºC
[ Exact Mass ]:
467.17900
[ PSA ]:
163.06000
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QD2840000
- CAS REGISTRY NUMBER :
- 34195-34-1
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C18-H21-N-O3.C4-H6-O6
- MOLECULAR WEIGHT :
- 449.50
- WISWESSER LINE NOTATION :
- T B6566 B6/CO 4ABBC R BX FV HO PN GHT&&TTJ JO1 P1 &OVYQYQVO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 375 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,42,1959 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 153 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- REFERENCE :
- AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920- Volume(issue)/page/year: 123,705,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80428 No. of Facilities: 2327 (estimated) No. of Industries: 3 No. of Occupations: 8 No. of Employees: 9115 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80428 No. of Facilities: 162 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 2238 (estimated) No. of Female Employees: 1177 (estimated)
Safety Information
[ RIDADR ]:
NONH for all modes of transport