6-Methyl-1H-indole

Names

[ Name ]:
6-Methyl-1H-indole

[Synonym ]:
6-Methyl-1H-indole
6-Methyl indole
Indole,6-methyl
6-Me-indole
MFCD00005682
6-Methylindole
Indole, 6-methyl-
6-Metlylindole
1H-Indole,6-methyl
1H-Indole, 6-methyl-

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
260.3±9.0 °C at 760 mmHg

[ Melting Point ]:
29-32°C

[ Molecular Formula ]:
C₉H₉N

[ Molecular Weight ]:
131.17

[ Flash Point ]:
109.6±11.3 °C

[ Exact Mass ]:
131.073502

[ PSA ]:
15.79000

[ LogP ]:
2.60

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.655

[ Storage condition ]:
0-6°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
UN 3334 9

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

trans-beta-dimethylamino-4-methyl-2-nitrostyrene
6-methylindoline
1,4-Dimethyl-2-nitrobenzene
1H-Indol-6-ylmethanol
Triethanolamine
3-Toluidine
1-[(E)-2-(4-methyl-2-nitrophenyl)vinyl]pyrrolidine
1-(2-bromo-2-chloroethyl)-4-methyl-2-nitrobenzene
TRIETHANOLAMINE HYDROCHLORIDE

DownStream

6-Methylgramine
6-Methyl-1H-indole-3-carbaldehyde
6-methylindoline
[1-(tert-butoxycarbonyl)-6-methyl-1H-indol-2-yl]boronic acid
TERT-BUTYL 6-METHYL-1H-INDOLE-1-CARBOXYLATE
6-Methyl-1H-indole-3-carboxylic acid
6-Methylisatin
Indole-6-carboxaldehyde
TERT-BUTYL 6-FORMYL-1H-INDOLE-1-CARBOXYLATE
6-(difluoromethyl)indole

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Total synthesis of 0231B, an inhibitor of 3alpha-hydroxysteroid dehydrogenase produced by Streptomyces sp. HKI0231.

Biosci. Biotechnol. Biochem. 67(3) , 659-62, (2003)

The new inhibitors of 3alpha-hydroxysteroid dehydrogenase, 0231A 1 and 0231B 2, have a unique benz[c,d]indol-3(1H)-one structure in their molecules. In our advanced studies on indole chemistry, we hav...