Benzyl hydroxycarbamate

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Names

[ CAS No. ]:
3426-71-9

[ Name ]:
Benzyl hydroxycarbamate

[Synonym ]:
Carbamic acid,hydroxy-,phenylmethyl ester
N-Hydroxycarbamic Acid Benzyl Ester
N-Z-Hydroxylamine,Benzyl N-hydroxycarbamate
N-carbobenzoxyhydroxylamine
N-(Benzyloxycarbonyl)hydroxylamine
Carbamic acid, N-hydroxy-, phenylmethyl ester
N-Z-Hydroxylamine
Benzyl hydroxycarbamate
N-Cbz-hydroxylamine
MFCD00010642

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
373.4±21.0 °C at 760 mmHg

[ Melting Point ]:
65-70 °C(lit.)

[ Molecular Formula ]:
C8H9NO3

[ Molecular Weight ]:
167.162

[ Flash Point ]:
179.6±22.1 °C

[ Exact Mass ]:
167.058243

[ PSA ]:
58.56000

[ LogP ]:
1.37

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.560

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FB1600000
CHEMICAL NAME :
Carbamic acid, hydroxy-, benzyl ester
CAS REGISTRY NUMBER :
3426-71-9
BEILSTEIN REFERENCE NO. :
1074034
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H9-N-O3
MOLECULAR WEIGHT :
167.18
WISWESSER LINE NOTATION :
QMVO1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
800 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 151,201,1985

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
FB1600000

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Benzyl chloroformate
  • Cbz-NH-O-Boc

DownStream

  • Dibenzyl carbonate
  • Benzyl 2-oxa-3-azabicyclo[2.2.1]hept-5-ene-3-carboxylate
  • benzyl N-phenylmethoxycarbamate
  • Benzyl carbamate
  • benzyl N-cyclohepta-1,3-dien-1-ylcarbamate
  • 1-Cbz-pyrrolidine
  • benzyl N-(2-hydroxy-2-phenylethyl)carbamate
  • Benzyl (2-hydroxy-1-phenylethyl)carbamate
  • benzyl N-oxocarbamate
  • n,o-bis-(benzyloxycarbonyl)-hydroxylamine

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

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A screen biased toward compounds containing zinc-binding groups (ZBG’s) delivered a number of micromolar inhibitors of DapE from Haemophilus influenzae, including l-captopril (IC 50 = 3.3 μM, K i = 1....


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Related Compounds

  • benzyl N-carbamoyl-N-hydroxycarbamate
  • benzyl N-3-trifluoromethylphenyl-N-hydroxycarbamate
  • benzyl N-4-cyanophenyl-N-hydroxycarbamate
  • benzyl (1R,2R)-2-formylcyclopentyl-N-hydroxycarbamate
  • benzyl-dimethyl-(2-prop-2-enoyloxyethyl)azanium,dimethyl-bis(prop-2-enyl)azanium,dichloride
  • Benzyl [2,4'-bipiperidine]-1-carboxylate hydrochloride
  • (E)-2-Cyano-3-[1-(1-methoxypropan-2-yl)-2,5-dimethylpyrrol-3-yl]-N-methylsulfonylprop-2-enamide
  • 6-Chloro-N-[4-[(Z)-(1-methylpyrrolidin-2-ylidene)amino]sulfonylphenyl]pyridine-3-carboxamide
  • 2-cyano-N-(3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonyl)-3-(furan-2-yl)prop-2-enamide
  • 3-ethoxy-2-[4-(1H-pyrazole-3-sulfonyl)piperazine-1-carbonyl]prop-2-enenitrile
  • ethyl 3-[1-(2-cyano-3-ethoxyprop-2-enamido)-3-methylbutyl]-1H-1,2,4-triazole-5-carboxylate
  • (Z)-2-Cyano-3-cyclopropyl-N-[3-[4-(3-methylphenyl)piperazin-1-yl]propyl]prop-2-enamide
  • (E)-2-Cyano-3-[2,5-dimethyl-1-(oxolan-2-ylmethyl)pyrrol-3-yl]-N-[1-(2H-tetrazol-5-yl)cyclopropyl]prop-2-enamide
  • 3-amino-2-cyano-3-(4-methylpiperidin-1-yl)-N-phenylprop-2-enamide
  • (2E)-2-(1,3-benzoxazol-2-yl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enenitrile
  • 3-[(E)-2-Cyano-3-oxo-3-(pyridin-4-ylamino)prop-1-enyl]benzoic acid
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