Ethyl 4-hydroxy-2-(trifluoromethyl)-5-pyrimidinecarboxylate

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Names

[ CAS No. ]:
343-67-9

[ Name ]:
Ethyl 4-hydroxy-2-(trifluoromethyl)-5-pyrimidinecarboxylate

[Synonym ]:
5-pyrimidinecarboxylic acid, 4-hydroxy-2-(trifluoromethyl)-, ethyl ester
ethyl 2-trifluoromethyl-4-hydroxypyrimidine-5-carboxylate
Ethyl 4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate
ethyl 4-hydroxy-2-trifluoromethylpyrimidine-5-carboxylate
ethyl 4-hydroxy-2-trifluorormethylpyrimidine-5-carboxylate
ethyl4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
220.8±40.0 °C at 760 mmHg

[ Melting Point ]:
315-316ºC

[ Molecular Formula ]:
C8H7F3N2O3

[ Molecular Weight ]:
236.148

[ Flash Point ]:
87.4±27.3 °C

[ Exact Mass ]:
236.040878

[ PSA ]:
72.31000

[ LogP ]:
1.26

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.475

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
48-20/21/22

[ Safety Phrases ]:
3/7/9-37/39

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Water
  • Diethyl ethoxymethylenemalonate
  • Trifluoroacetamideine

DownStream

  • ETHYL 4-HYDRAZINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE
  • 2-(trifluoromethyl)pyrimidine-5-carbaldehyde
  • Ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate
  • Ethyl 4-chloro-2-trifluoromethylpyrimidine-5-carboxylate

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 3,4-Dimethyl-(4H)1,4-benzothiazine-1,1-dioxide
  • 4-Fluoro-3-nitrophenyl methanesulfonate
  • 3-Fluoro-4-methanesulfonylbenzamide
  • 8-Fluoroquinoline-5-carbonitrile
  • 4-Fluoro-2-nitrophenyl methanesulfonate
  • 4-[2-(2-Methyl-4-nitrophenoxy)ethyl]morpholine
  • 4-Chloro-3-[(4-methoxyphenyl)methoxy]benzaldehyde
  • 2-(N,N-BisBoc-amino)-5-chloro-3-iodopyridine
  • 5-Bromo-2-(2-methoxyethoxy)-3-(trifluoromethyl)pyridine
  • 5-Bromo-2-(cyclopentyloxy)-3-(trifluoromethyl)pyridine