2,6-Dibromo-4-fluoroaniline

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Names

[ CAS No. ]:
344-18-3

[ Name ]:
2,6-Dibromo-4-fluoroaniline

[Synonym ]:
Benzenamine, 2,6-dibromo-4-fluoro-
2,6-dibromo-4-fluoro-phenylamine
2-Amino-1,3-dibromo-5-fluorobenzene
2,6-Dibromo-4-fluoroaniline
1-amino-2,6-dibromo-4-fluorobenzene
2,6-Dibrom-4-fluor-anilin
2,6-dibromo-4-fluoro-aniline
2,6-Dibromo-4-fluorobenzenamine
MFCD00041445

Chemical & Physical Properties

[ Density]:
2.1±0.1 g/cm3

[ Boiling Point ]:
265.2±35.0 °C at 760 mmHg

[ Melting Point ]:
64-66 °C(lit.)

[ Molecular Formula ]:
C6H4Br2FN

[ Molecular Weight ]:
268.909

[ Flash Point ]:
114.2±25.9 °C

[ Exact Mass ]:
266.869446

[ PSA ]:
26.02000

[ LogP ]:
3.60

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.634

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39

[ RIDADR ]:
UN2811

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2921420090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Fluoroaniline
  • 5-Fluoroorthanilic acid (SO3H=1)
  • 4'-fluoroacetanilide
  • Water
  • Bromine

DownStream

  • 7-Bromo-5-fluoro-3-methyl-1H-indole
  • 1,3-Dibromo-5-fluoro-2-iodobenzene
  • (2E)-3-(5-FLUORO-3-METHYL-1H-INDOL-7-YL)- 2-PROPENOIC ACID
  • N-Allyl-2,6-dibromo-4-fluoroaniline
  • 1,3-dibromo-5-fluoro-2-methylsulfanylbenzene

Customs

[ HS Code ]: 2921420090

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Asymmetric synthesis of a prostaglandin D2 receptor antagonist.

J. Org. Chem. 70(1) , 268-74, (2005)

An asymmetric synthesis was developed for the production of a prostaglandin D(2) receptor antagonist for the treatment of allergic rhinitis. The stereogenic center was set using asymmetric allylic alk...


More Articles

Related Compounds

  • N-Allyl-2,6-dibromo-4-fluoroaniline
  • 3-chloro-2,6-dibromo-4-fluoroaniline
  • 1-N-allyl-2,6-dibromo-4-fluoroaniline
  • 2,6-dibromo-3,5-dichloro-4-fluoroaniline
  • 2,6-dibromo-4-methylsulfonylaniline
  • 2,6-dibromo-4-[hydroxy(diphenyl)methyl]phenol
  • (E)-4-(Dimethylamino)-N-[2-(5-phenylimidazol-1-yl)ethyl]but-2-enamide
  • (E)-4-(Dimethylamino)-N-(4-pyrazin-2-yloxycyclohexyl)but-2-enamide
  • (E)-4-(Dimethylamino)-N-(1H-pyrrolo[2,3-b]pyridin-6-ylmethyl)but-2-enamide
  • 4-(But-2-ynoylamino)-N,N-dimethylcyclohexane-1-carboxamide
  • Tert-butyl 3-[2-(but-2-ynoylamino)ethoxy]pyrrolidine-1-carboxylate
  • Tert-butyl 3-[2-(2-chloroacetamido)ethyl]thiomorpholine-4-carboxylate
  • N-[2-(2,5-Dihydropyrrol-1-yl)ethyl]-N-ethylbut-2-ynamide
  • N-(2-{bicyclo[2.2.1]heptan-2-yl}-6-oxopiperidin-3-yl)but-2-ynamide
  • Methyl (E)-4-oxo-4-[1-[5-(phenoxymethyl)-1,2,4-oxadiazol-3-yl]ethylamino]but-2-enoate
  • sodium 4-(2,5-diphenyl-1H-pyrrol-1-yl)benzoate
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